Springbok captain Victor Matfield paid tribute to his side's staunch defence as the world champions withstood a late rally from Wales to win 25-29 at the Millennium Stadium.
The victory kept South Africa's hopes of a Grand Slam alive after they brushed aside Ireland last weekend.
South Africa were 17-9 behind at the break but scored 17 unanswered points in the space of seven minutes to grab the initiative from Wales.
Wales refused to cave in and mounted a fierce late rally but couldn't breach the green wall.
"I'm very proud of the boys, they showed great character," said Matfield. "Wales put us under pressure and it was a great game for the spectators to watch.
"Well done to Wales, they really came out and played well. "(Defending) is something we really worked hard on (in training) and it came through and we were happy with that," he added.
Referring to a possible Grand Slam, Matfield said: "I don't know. There's still a fair way to go. We're focusing on Scotland and that's going to be another huge game. We will enjoy tonight and then start fresh from zero on Monday again."
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Cardiff managed to keep their unbeaten record at home intact, but only just as Bridgend made them work extremely hard before the Blue and Blacks secured a hard fought Principality Premiership win at the BT Sport Arms Park last night.
Former Wales back row Andy Powell gives a guided tour of The Wern, home of Merthyr RFC, who are determined to prove a lot of people wrong and make their mark in their first season in the Principality Premiership.
Wales Sevens head coach Gareth Williams looks back on the Rio Sevens success where he helped GB win silver. He believes the successful campaign is a huge boost to his Welsh squad as they prepare for another World Series, as WRU TV's Graeme Gillespie discovers
British and Irish Lions head coach Warren Gatland will be heading back home to take on the All Blacks next year where for him, success for 2017 is all about going to New Zealand and winning a Test Series.
Last week all roads led to Eugene Cross Park where defending champions Ebbw Vale hosted this season's launch of the Principality Premiership. WRU TV's Graeme Gillespie was there to capture the thoughts of Damien Hudd, captain of Ebbw Vale, and WRU Head of Performance, Geraint John.
Llandovery made it three in a row when they defeated Aberavon in the final of the National Foster's 7s at BT Sport Cardiff Arms Park on Sunday. On another eventful day of sevens, Newport claimed the Plate and the Dragons won the women's crown
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Wales Under 18 captain Callum Bradbury is delighted to have seen his side claim a narrow 18-17 victory against a strong SA Schools 'A' side to end the three-match Under 19 International Series in South Africa on a high note.