Two South African players have been suspended and sent home after testing positve for a banned substance
Springboks duo Chiliboy Ralepelle and Bjorn Basson have both been suspended and sent home to South Africa after failing drugs tests.
Both players featured in Saturday's 29-25 victory against Wales before the South African Rugby Union was notified of the positive tests late on Sunday evening.
The players tested positive for a banned stimulant after their narrow 23-21 victory over Ireland the previous weekend.
Six Nations Rugby Ltd, which administers the November internationals, informed the South Africa of its findings and as a result the pair have been sent home from the Springboks' European tour.
Basson had already been ruled out of the remainder of the tour after suffering an ankle injury during the Millennium Stadium victory. The 23-year-old wing is the record holder for the most tries in a Currie Cup campaign.
24-year-old hooker Ralepelle has made 17 international appearances and was the first black player to captain the national side when he led them out against a World XV in Leicester.
Both players tested positive for methylhexaneamine, a "non-specified stimulant" on the prohibited substances list of the World Anti-Doping Agency (Wada).
Methylhexaneamine is scheduled to be reclassified as a "specified stimulant" from 1 January 2011.
The players have the right to request that their 'B' sample be tested.
WRU International Skills Coach Jason Strange is a busy man, combining the new role with that of Wales Under 20 attack coach, Ebbw Vale head coach and continuing to teach at Ebbw Fawr Learning Community.
Warren Gatland and Sam Warburton look ahead to this week's crunch RBS 6 Nations tie against France, where the Wales skipper in particular is keen to make his mark, as Paris has proved a bleak place for him in the past.
Following their historic win over England, Wales Under 20 suffered a narrow, 36-34 loss to their Scottish counterparts last weekend, despite outscoring them by five tries to three. Watch the match highlights and reaction.
WRU TV go behind the scenes with the Wales squad as they put the final touches in place ahead of the clash against Scotland at Murrayfield. Follow the squad on their captain's run, the kickers visit to Murrayfield and Neil Jenkins' press conference