Hard running centre Adi Taviner will captain Wales U20s against England.
Wales Women Under 20s are hoping to turn the tables on arch rivals England in an international clash at Taffs Well on Sunday (KO 2pm).
The red rose brigade had to dig deep to repel the challenge of Wales two weeks ago to scrape home with a 17-7 victory. Kylie Wilson's team are determined to build on their excellent first half performance from last time out but will have to turn pressure into points if they are to reverse the result.
Wales coach Wilson, said: "The coaching team are excited to see some new players enter the squad, confirming the improved depth at this age group within Wales through the new regional programme.
"[Utility back] Megan Williams was identified through the Dragons and will be keen to earn her first cap."
Williams, along with fellow replacements Natalie Stone and Rebecca Norris will earn their first Welsh caps if they get off the bench.
Half of the Welsh squad will be playing their last game at this level before moving up to the senior ranks. With just one more round of regional games remaining before Jason Lewis announces his World Cup squad, Sunday's encounter offers the players a chance to impress.
Wales have selected a physical pack to combat the strong English unit while the backline has been re-shuffled after centre Jess Smith was ruled out due to injury.
Jess Kavanagh comes in at wing with Charlotte Murray moving to outside centre while captain Adi Taviner shifts to inside centre.
Wales manager Sara Davies, said: "Many of the players will be playing their last game at U20 level so they will be determined to leave on a high and put in a performance that earns Wales their first victory over the old enemy at this level.
"Some may have one eye on World Cup selection so that will ensure they give 100 per cent so hopefully that will inspire them to a victory," she added.
Wales Women's Under 20s
15 Kerin Lake (Neath Athletic)
14 Sian Perry (Altrincham Kersal)
13 Charlotte Murray (Neath Athletic)
12 Adi Taviner (Neath Athletic)
11 Jess Kavanagh (Dolgellau)
10 Bethan Preece (Neath Athletic)
9 Yasmin Leung (UWIC)
1 Alex Stokes (Neath Athletic)
2 Amy Lawrence (Neath Athletic)
3 Lowri Harris (UWIC)
4 Chloe Howells (Whitland)
5 Shona Powell-Hughes (Neath Athletic)
6 Sian Williams (RAF)
8 Vicky Owens (UWIC)
7 Sioned Harris (UWIC)
16 Natalie Stone (Pontyclun)
17 Sophie Mangano (Kidwelly)
18 Rebecca Norris (Carmarthen Quins)
19 Kathryn Joseph (Neath Athletic)
20 Kayleigh Balchin (Longton)
21 Megan Williams (OA Saints)
22 Rhianydd Morgan (Neath Athletic)
England Under 20s 15 Kay Wilson (Richmond) 14 Rebecca Hughes (Bristol) 13 Amy Wilson Hardy (Hove) 12 Amber Reed (Bristol) 11 Sophie Watkiss (Worcester) 10 Emily Scott 9 Fiona Davidson (Richmond); 1 Sasha Acheson (Shelford) 2 Vicky Fleetwood (Lichfield) 3 Charlotte Male (Bristol - capt) 4 Amy Millar (Worcester), 5 Stacey Maguire (Lichfield), 6 Poppy Cleall (Ellingham & Ringwood), 7 Hannah Field (Wasps), 8 Nicola Hoole (Bristol).
Replacements: 16 Geraldine Thomas (OA Saints), 17 Mille Fuggles (OA Saints), 18 Sarah George (Univeristy of Exeter), 19 Marlie Packer (Bristol), 20 Hannah Gallagher (Saracens), 21 Jessie flowers (Oxford University), 22 Garnet Mackinder (Lichfield).
Wales Head Coach Rob Howley talks to WRU TV's Sebastian Barrett about the 36-man squad he has just named for the forthcoming Under Armour series, which includes two uncapped players, Ospreys duo Sam Davies and Rory Thornton.
Head coach Rowland Phillips is deligthed he can now call BT Sport Cardiff Arms Park home for his Wales Women's side, who launch their international season next month with games against Scotland and UK Armed Forces in the heart of the capital city.
Wales Sevens star Sam Cross has put his home town club of Brynmawr on the map after winning a silver medal at the Rio Olympics with Team GB. His club have now honoured him by naming their players bar after him, as WRU TV discovered at the official launch, recently.
One of the newest members of the Principality Premiership, Bargoed admit it's proving to be a steep learning curve at the highest level, but are determined to become a force to be reckoned with. WRU TV visited the club last weekend when they took on Llanelli.
Table-topping Aberavon travel to north Wales to tackle RGC 1404 as both teams defend unbeaten starts to the season in the Principality Premiership. WRU TV's Graeme Gillespie visited the Wizards to see how their preparations were going for the game of the weekend.
The Half a Game initiative is currently sweeping across Wales and proving a major success. The scheme aims to give every young player at least half a game every weekend. WRU TV recently visited a festival in Narberth where clubs have fully embraced the initiative.
Both Bargoed and Swansea were seeking their first win of the Principality Premiership season this afternoon. It proved a fruitful day for the hosts - not only did they win, but Bargoed claimed a try bonus point.
Cardiff managed to keep their unbeaten record at home intact, but only just as Bridgend made them work extremely hard before the Blue and Blacks secured a hard fought Principality Premiership win at the BT Sport Arms Park last night.
Former Wales back row Andy Powell gives a guided tour of The Wern, home of Merthyr RFC, who are determined to prove a lot of people wrong and make their mark in their first season in the Principality Premiership.