Gavin Thomas, who has been outstanding since joining the Dragons from the Scarlets, will be looking to impress again against the Ospreys.
Paul Turner has announced a 25 man squad in preparation for Friday evening's Magners League match with the Ospreys at the Liberty Stadium (KO 7:05pm).
Looking forward to the Dragons final game of the season head coach Paul Turner said: "Many of the young players included in the squad are our future and have a great opportunity to press their cases. We've been really pleased with the likes of Andrew Coombs and Lloyd Burns who have stepped up to the plate this season, gaining valuable experience.
"We have a great environment for youngsters here, the new training facility is excellent and real progress is being made. The players that have stuck with us have shown real improvement and are being well coached.'"
Dragons captain Tom Willis is relishing the prospect of another Welsh derby.
''It would be great to finish the season with another big scalp, but we understand that they will be hurting from what happened to them here back in March. There's no doubt that they will put out a strong team. But we have fought hard this season to gain respect and we don't want to throw that away this weekend.
"This league is about squads, but we have been well supported by the Principality Premiership teams in our Region, and the Academy have played a significant role too.
'We're happy with direction we are going and we're going at a good speed. There are still things to work on, such as our away form, but overall we're on the right track.'
Scrum-half, Wayne Evans added 'The Ospreys present another great opportunity to perform against some class players.
Backs: Adam Hughes, Will Harries, Rhodri Gomer Davies, Pat Leach, Richard Fussell, Jason Tovey, Lewis Robling, Jonathan Evans, Adam Greendale, Wayne Evans, Tom Riley, Matthew Pewtner
Forwards: Lewis Evans, Pat Palmer, Tim Willis, Toby Faletau, Andrew Coombs, Hoani MacDonald, Ben Castle, Rob Sidloi, Gavin Thomas, Lloyd Burns, Jevon Groves, Aaron Coundley, James Harris.
As the countdown continues for RWC2015, Tournament Chief Executive Debbie Jevans visited the Millennium Stadium to discuss preparations for the eight matches and reveal the positive news that 100,000 tickets for games at the home of Welsh rugby have sold in the last seven days.
Jason Harries is targeting a first win on the World Series circuit this season with Wales. The series returns to action this weekend in Dubai where Harries is part of a team hoping to build from its efforts in round one in October.
Wales skipper Jevon Groves says his side have addressed a few points from Gold Coast and aim to 'hit the ground running' in the next two rounds of the World Series, kicking off with this weekend in Dubai before heading off to South Africa next week.
Wales Sevens manager Steff Thomas is hopeful his side can build from a quarter-final spot in the opening round of the World Series in Australia when his side take part in the forthcoming double header in Dubai and South Africa.