Blues prop Gethin Jenkins is set to make his 100th appearance for the region tomorrow when his side take on the Scarlets.
Blues head coach David Young has made two changes to the team that defeated Newcastle Falcons for the match against the Scarlets on Saturday.
Second row forward, Paul Tito, returns to the starting line up with Bradley Davies dropping down to the bench. In the front row, Gareth Williams starts at hooker with Rhys Thomas also moving down to the bench.
Gethin Jenkins makes his 100th appearance for the Blues having joined the region in the summer of the 2004.
The Blues travel to Parc y Scarlets boosted by two big away wins, having recorded a 33-24 win over Ulster at Ravenhill in the Magners League and 55-20 win over Newcastle Falcons in the north east of England in the Amlin Cup. Even more impressively the Blues have also won their last five away encounters.
They will be buoyed by the fact they have beaten Scarlets twice already this season, 19-15 at Cardiff City Stadium in the Magners League and 38-23 at Parc y Scarlets in the Anglo-Welsh Cup.
Blues talisman Martyn Williams reckons Cardiff Blues face their toughest game of the year when they take on Scarlets.
With Heineken Cup qualification on the line for both sides, Wales flanker Williams is braced for a fierce Welsh derby.
Williams said: "This will be the toughest game of the year for us because we don't have a great record at Llanelli and because of what is at stake for the Scarlets.
"They know they will be out of the running for qualification if they lose and that will really drive them on."
The Blues have won just one of their last seven games at the west Wales region but travel on the back of reaching the semi-finals of the Amlin Challenge Cup with an emphatic 55-20 demolition of Newcastle Falcons.
Williams said: "We are going into the game on a high after a good performance against Newcastle. We played some good rugby, albeit against a pretty poor defence. But we will build on that confidence for a tough game."
Scarlets Head Coach Nigel Davies has opted for a few changes to the team that started in Toulon and this week told his players to "stand up and be counted" after a disappointing display in the South of France.
British Lions and Wales international hooker Matthew Rees does not make the fitness race due to a minor neck injury, with Ken Owens starting for the Scarlets in the big derby.
Daniel Evans starts at full-back ahead of Rhys Priestland who is on the bench - the only change in the backs from last weekend's team. Rhys Thomas starts at tighthead prop with Deacon Manu on the bench. Tavis Knoyle gets the scrum-half jersey and Josh Turnbull comes in at flanker with Rob McCusker on the bench.
Davies said: "We lacked urgency last weekend and will be putting that right for this game, Cardiff are playing some good rugby - they are scoring tries and showing the quality they have in their squad.
"We know we are going to have to defend well, they have some big ball carriers, who get them over the advantage line and give them good go forward ball, some very useful backs and key strike players that we'll have to manage."
Blues 15 Ben Blair 14 Leigh Halfpenny 13 Casey Laulala 12 Jamie Roberts 11 Chris Czekaj 10 Ceri Sweeney 9 Richie Rees 8 Xavier Rush 7 Martyn Williams 6 Maama Molitika 5 Paul Tito (c) 4 Deiniol Jones 3 Taufa'au Filise 2 Gareth Williams 1 Gethin Jenkins
Replacements: 16 T Rhys Thomas 17 John Yapp 18 Bradley Davies 19 Sam Warburton 20 Lloyd Williams 21 Dai Flanagan 22 Dafydd Hewitt
Scarlets 15 Daniel Evans, 14 Sean Lamont, 13 Regan King, 12 Jonathan Davies 11 Andy Fenby, 10 Stephen Jones, 9 Tavis Knoyle, 1 Phil John, 2 Ken Owens, 3 Rhys Thomas, 4 Lou Reed, 5 Dominic Day, 6 Josh Turnbull, 7 Richie Pugh, 8 David Lyons (capt).
Replacements: 16 Deacon Manu, 17 Emyr Phillips, 18 Damian Welch 19 Rob McCusker, 20 Martin Roberts, 21 Rhys Priestland, 22 Lee Williams.
Wales 7s Manager Steff Thomas believes Luke Treharne has all the attriubutes to be a top class captain. WRU TV's Graeme Gillespie hears his reasons why as the squad prepare for the opening two legs of the new World Series in Dubai and South Africa.
The British & Irish Cup kicks off this weekend with the four Regional Premiership Select XVs flying the flag for Wales. Welsh
Sat 14 Nov: Blues Premiership Select v Nottingham (2.30) & Connacht Eagles v Dragons (2.30)
Sun 15 Nov: Yorkshire Carnegie v Ospreys Premiership Select (1.30) & Scarlets v Bedford Blues (3.00)
The Welsh Rugby Union is forming a new Youth Board with a brief to help keep more young people involved in the game during their late teenage years and beyond. The first task of the fifteen strong Board will be to analyse and consider the issues which lead to a number of youngsters drifting away from the sport between the ages of 16 and 21. To apply visit www.wru.wales/youthboard
The Foster's Challenge Cup will involve the 12 Principality Premiership sides and will run during European and British & Irish Cup weeks, providing vital fixtures for the participating clubs and an opportunity for upcoming players to step up to semi-professional rugby and make a claim for starting places within the Premiership squads.
Eighty schools and colleges in Wales now have a full time rugby officer as part of the WRU's school club hub scheme. All of the school club hub officers recently gathered at the National Centre of Excellence for various workshops.
With Liam Williams forced out of the World Cup through injury, lock Luke Charteris and Skills Coach Neil Jenkins say they have to put yesterday's defeat behind them as Wales now look ahead to another physical encounter against South Africa in the quarter-finals of the Rugby World Cup.
WRU Consultant Head of Physical Performance Paul Stridgeon praises the Physical Performance department for their work and dedication as he addresses the media ahead of Wales' Pool A clash against Australia
Twelve young people have been selected to follow a one year WRU Coach Core apprenticeship programme. Coach Core was set up by the Royal Foundation of the Duke and Duchess of Cambridge and Prince Harry as part of the Olympics legacy in 2012 and the Duke of Cambridge was on hand to meet the apprentices on their first day in the job. The programme has been funded by the Hunter Foundation.