Glamorgan Wanderers travel to the Gnoll for the second time in a month on Saturday
"We expect a backlash after putting them out of the cup but we need our heads to rule our hearts and blank out all the off the field nonsense," commented coach Richard Hodges on the challenge ahead.
"Currently top of the Principality Premiership, Neath will be concentrating on winning back the league title now after their exit from the cup."
The Wanderers will be looking to bounce back after the home defeat to Cross Keys with Dan Fish, Josh Navidi and Ieuan Davies involved with the Wales Under 20s Hodges shuffles his squad again.
Owen Marshall starts at 15 and Harry Trelawny returns as captain at scrum half in a back division that shows two changes from the side that beat Neath. In the pack a late decision will be made in the front row but Jim Richards returns at hooker on a ground that has many memories for him.
Lee Highgate, Ben Rose and Mazin Al-Azzawi continue in the back row and Mark O'Leary returns after intense physio treatment on his shoulder injury.
Glamorgan Wanderers 15. Owen Marshall 14. Steve Cullen 13. Simon Rosser 12. Charlie Johnson 11. Rory Budina 10. Scott Sneddon 9. Harry Trelawny; 1. Mark O'Leary 2. James Richards 3. Danny Douthwaite/ Ryan Beddows 4. Gareth Knight 5. John Barley 6. Lee Highgate 7. Ben Rose 8. Mazin Al-Azzawi
Replacements: 16. Ieuan Dobbs 17. Ryan Beddows / Danny Douthwaite 18. Richard Thomas 19. A.N.Other 20. Ross Wardle 22. Rhys Dyer 24. Ryan Healey
Wales Head Coach Rob Howley talks to WRU TV's Sebastian Barrett about the 36-man squad he has just named for the forthcoming Under Armour series, which includes two uncapped players, Ospreys duo Sam Davies and Rory Thornton.
Head coach Rowland Phillips is deligthed he can now call BT Sport Cardiff Arms Park home for his Wales Women's side, who launch their international season next month with games against Scotland and UK Armed Forces in the heart of the capital city.
Wales Sevens star Sam Cross has put his home town club of Brynmawr on the map after winning a silver medal at the Rio Olympics with Team GB. His club have now honoured him by naming their players bar after him, as WRU TV discovered at the official launch, recently.
One of the newest members of the Principality Premiership, Bargoed admit it's proving to be a steep learning curve at the highest level, but are determined to become a force to be reckoned with. WRU TV visited the club last weekend when they took on Llanelli.
Table-topping Aberavon travel to north Wales to tackle RGC 1404 as both teams defend unbeaten starts to the season in the Principality Premiership. WRU TV's Graeme Gillespie visited the Wizards to see how their preparations were going for the game of the weekend.
The Half a Game initiative is currently sweeping across Wales and proving a major success. The scheme aims to give every young player at least half a game every weekend. WRU TV recently visited a festival in Narberth where clubs have fully embraced the initiative.
Both Bargoed and Swansea were seeking their first win of the Principality Premiership season this afternoon. It proved a fruitful day for the hosts - not only did they win, but Bargoed claimed a try bonus point.
Cardiff managed to keep their unbeaten record at home intact, but only just as Bridgend made them work extremely hard before the Blue and Blacks secured a hard fought Principality Premiership win at the BT Sport Arms Park last night.
Former Wales back row Andy Powell gives a guided tour of The Wern, home of Merthyr RFC, who are determined to prove a lot of people wrong and make their mark in their first season in the Principality Premiership.