Leigh Halfpenny scores against Scotland in last season's championship
Wales have made two changes from the starting line-up defeated by England at Twickenham in the RBS 6 Nations opener last weekend for the visit of Scotland to the Millennium Stadium on Saturday (kick-off 2.00pm).
In the second row, Osprey Jonathan Thomas reforms his regional partnership with Alun-Wyn Jones at the expense of Dragons lock Luke Charteris. In the backs Leigh Halfpenny comes in for his Blues colleague Tom James on the wing.
Gethin Jenkins has recovered from his calf injury to be named on the bench and, in one of three changes there, he joins fellow Blues players Sam Warburton, who covers the back row, and centre or wing Tom Shanklin.
"Jonathan brings over 50 caps of experience to the tight five and offers us some extra mobility around the field," said Wales coach Warren Gatland.
"Leigh is a recognised right wing who offers us an extra kicking option and his return to full fitness after limited training in the run up to the England game allows his selection.
"We think we have a very strong bench with the right mix of players each able to make an impact if called upon and are pleased to be able to name Gethin although he will undergo further fitness assessments later in the week.
"Tom Shanklin returns to provide another 65-caps worth of experience as cover for the backs and Sam Warburton comes in as back row cover with JT (Jonathan Thomas) now having been nominated as a starting second row."
Ryan Jones captains Wales for the 21st time taking him to joint fourth in the all-time list alongside Gareth Thomas and behind Rob Howley and Colin Charvis (22) and Ieuan Evans (28).
And fellow back row forward Martyn Williams reaches two more landmarks, winning his 93rd cap, to put him in third place on the all-time appearance list behind Charvis (94) and Thomas (100), and making his 49th tournament appearance - a Welsh record - putting him in line to become only the eighth player to play 50 championship matches.
"We were all disappointed with the result last weekend but the good news for these players is that they have an opportunity now, just seven days after losing a game we all feel we could have won, to bounce back against Scotland," added Gatland.
"The championship is by no means over and we are back home at the Millennium Stadium on Saturday looking to kick-start our campaign.
"This is a must win game for us and the Millennium Stadium factor will have a big part to play, as will the fans, and we are all very much looking forward to coming home."
WALES: Lee Byrne; Leigh Halfpenny, James Hook, Jamie Roberts, Shane Williams; Stephen Jones, Gareth Cooper; Paul James, Gareth Williams, Adam Jones, Jonathan Thomas, Alun Wyn Jones, Andy Powell, Martyn Williams, Ryan Jones (Captain)
REPLACEMENTS: Huw Bennett, Gethin Jenkins, Bradley Davies, Sam Warburton, Richie Rees, Andrew Bishop, Tom Shanklin
Wales U20 duo Leon Brown and Lloyd Lewis face a busy couple of weeks ahead. Not only will they have a Junior World Championship to take part in, they are both sitting A Level exams during the competition.
Wales U20 face a tough group in the Junior World Championship with France, England and Japan lying in wait but Attack coach Jason Strange and back rower Tom Phillips are looking forward to the campaign ahead.
Angus O'Brien has quickly settled into the Wales Sevens squad after solid performances in Hong Kong and Japan. With two rounds remaining in Glasgow and Twickenham on the World Series, WRU TV's Graeme Gillespie chats to the rising star.
Wales winger Luke Morgan has established himself as one of the deadliest finishers on the Sevens World Series. WRU TV's Graeme Gillespie catches up with him on the eve of this weekend's round in Glasgow.
All roads lead to Cardiff on Sunday for the SSE SWALEC Finals Day at the Millennium Stadium. Cambrian Welfare tackle Ystradgynlais in the Bowl final, Ystrad Rhondda play Newcastle Emlyn in the Plate final while defending champions Pontypridd face Bridgend in the Cup final.
WRU Chief Executive Roger Lewis, Deputy Minister for Culture, Sport and Tourism Ken Skates and WRU Chairman Gareth Davies earlier this week launched a new competition in conjunction with the WRU unveiling its archive room.
Welsh players and management joined Deputy Minister for Sport Ken Skates at the Pierhead Building, Cardiff Bay earlier this week to reveal the Union's pioneering school-club hub initiative has been so successful the project will now almost double the scale of the original project.
The Scarlets, Newport Gwent Dragons, Cardiff Blues and the Ospreys look ahead to Judgement Day III which sees the Blues take on the Ospreys (2.30) and the Dragons tackle the Scarlets (4.45pm) at the Millennium Stadium tomorrow afternoon.
Ystradgynlais and Ynysddu played out a titanic struggle at Taffs Well in the SSE SWALEC Bowl semi-final. At the end of the game neither team could be separated after a 15-15 stalemate but Ystradgynlais go through on try count.