Dai Young will be urging his side to "go for the jugular" against Harlequins next weekend as they try to make three seasons in a row of European quarter-final action.
The Blues were devastated when they were knocked-out of the Heineken Cup semi-finals last season in a penalty shoot-out against Leicester Tigers.
Now they have to hope Harlequins can do them a favour by beating Toulouse in France this weekend to keep alive their dreams of making it through to the last eight of the Heineken Cup again.
But even if that option is cut-off, they can still reach the quarter-finals of the re-structured Amlin Challenge Cup if they can win at the Twickenham Stoop. Their 36-19 home win over Sale Sharks moved them into second place in the Pool and ready to pounce if three-times winners Toulouse slip up in the final two rounds.
"It was a really professional performance from the players. They delivered a game that we had talked about and prepared for," said Blues coach Dai Young.
"We wanted to take them on physically up front and our driving line-out and scrum caused them problems. Now we have to hope Harlequins can do us a favour in Toulouse this weekend.
"All we can do now is concentrate on winning in London next week. If we can do that then we're still in with a chance of going through into a European quarter-final.
"If it is the Heineken Cup, then great. If it is the Amlin Challenge Cup, then we will give that a good crack as well."
Wales Head Coach Rob Howley talks to WRU TV's Sebastian Barrett about the 36-man squad he has just named for the forthcoming Under Armour series, which includes two uncapped players, Ospreys duo Sam Davies and Rory Thornton.
Head coach Rowland Phillips is deligthed he can now call BT Sport Cardiff Arms Park home for his Wales Women's side, who launch their international season next month with games against Scotland and UK Armed Forces in the heart of the capital city.
Wales Sevens star Sam Cross has put his home town club of Brynmawr on the map after winning a silver medal at the Rio Olympics with Team GB. His club have now honoured him by naming their players bar after him, as WRU TV discovered at the official launch, recently.
One of the newest members of the Principality Premiership, Bargoed admit it's proving to be a steep learning curve at the highest level, but are determined to become a force to be reckoned with. WRU TV visited the club last weekend when they took on Llanelli.
Table-topping Aberavon travel to north Wales to tackle RGC 1404 as both teams defend unbeaten starts to the season in the Principality Premiership. WRU TV's Graeme Gillespie visited the Wizards to see how their preparations were going for the game of the weekend.
The Half a Game initiative is currently sweeping across Wales and proving a major success. The scheme aims to give every young player at least half a game every weekend. WRU TV recently visited a festival in Narberth where clubs have fully embraced the initiative.
Both Bargoed and Swansea were seeking their first win of the Principality Premiership season this afternoon. It proved a fruitful day for the hosts - not only did they win, but Bargoed claimed a try bonus point.
Cardiff managed to keep their unbeaten record at home intact, but only just as Bridgend made them work extremely hard before the Blue and Blacks secured a hard fought Principality Premiership win at the BT Sport Arms Park last night.
Former Wales back row Andy Powell gives a guided tour of The Wern, home of Merthyr RFC, who are determined to prove a lot of people wrong and make their mark in their first season in the Principality Premiership.