Dai Young will be urging his side to "go for the jugular" against Harlequins next weekend as they try to make three seasons in a row of European quarter-final action.
The Blues were devastated when they were knocked-out of the Heineken Cup semi-finals last season in a penalty shoot-out against Leicester Tigers.
Now they have to hope Harlequins can do them a favour by beating Toulouse in France this weekend to keep alive their dreams of making it through to the last eight of the Heineken Cup again.
But even if that option is cut-off, they can still reach the quarter-finals of the re-structured Amlin Challenge Cup if they can win at the Twickenham Stoop. Their 36-19 home win over Sale Sharks moved them into second place in the Pool and ready to pounce if three-times winners Toulouse slip up in the final two rounds.
"It was a really professional performance from the players. They delivered a game that we had talked about and prepared for," said Blues coach Dai Young.
"We wanted to take them on physically up front and our driving line-out and scrum caused them problems. Now we have to hope Harlequins can do us a favour in Toulouse this weekend.
"All we can do now is concentrate on winning in London next week. If we can do that then we're still in with a chance of going through into a European quarter-final.
"If it is the Heineken Cup, then great. If it is the Amlin Challenge Cup, then we will give that a good crack as well."
The British & Irish Cup kicks off this weekend with the four Regional Premiership Select XVs flying the flag for Wales. Welsh
Sat 14 Nov: Blues Premiership Select v Nottingham (2.30) & Connacht Eagles v Dragons (2.30)
Sun 15 Nov: Yorkshire Carnegie v Ospreys Premiership Select (1.30) & Scarlets v Bedford Blues (3.00)
The Welsh Rugby Union is forming a new Youth Board with a brief to help keep more young people involved in the game during their late teenage years and beyond. The first task of the fifteen strong Board will be to analyse and consider the issues which lead to a number of youngsters drifting away from the sport between the ages of 16 and 21. To apply visit www.wru.wales/youthboard
The Foster's Challenge Cup will involve the 12 Principality Premiership sides and will run during European and British & Irish Cup weeks, providing vital fixtures for the participating clubs and an opportunity for upcoming players to step up to semi-professional rugby and make a claim for starting places within the Premiership squads.
Eighty schools and colleges in Wales now have a full time rugby officer as part of the WRU's school club hub scheme. All of the school club hub officers recently gathered at the National Centre of Excellence for various workshops.
With Liam Williams forced out of the World Cup through injury, lock Luke Charteris and Skills Coach Neil Jenkins say they have to put yesterday's defeat behind them as Wales now look ahead to another physical encounter against South Africa in the quarter-finals of the Rugby World Cup.
WRU Consultant Head of Physical Performance Paul Stridgeon praises the Physical Performance department for their work and dedication as he addresses the media ahead of Wales' Pool A clash against Australia
Twelve young people have been selected to follow a one year WRU Coach Core apprenticeship programme. Coach Core was set up by the Royal Foundation of the Duke and Duchess of Cambridge and Prince Harry as part of the Olympics legacy in 2012 and the Duke of Cambridge was on hand to meet the apprentices on their first day in the job. The programme has been funded by the Hunter Foundation.