Dai Young will be urging his side to "go for the jugular" against Harlequins next weekend as they try to make three seasons in a row of European quarter-final action.
The Blues were devastated when they were knocked-out of the Heineken Cup semi-finals last season in a penalty shoot-out against Leicester Tigers.
Now they have to hope Harlequins can do them a favour by beating Toulouse in France this weekend to keep alive their dreams of making it through to the last eight of the Heineken Cup again.
But even if that option is cut-off, they can still reach the quarter-finals of the re-structured Amlin Challenge Cup if they can win at the Twickenham Stoop. Their 36-19 home win over Sale Sharks moved them into second place in the Pool and ready to pounce if three-times winners Toulouse slip up in the final two rounds.
"It was a really professional performance from the players. They delivered a game that we had talked about and prepared for," said Blues coach Dai Young.
"We wanted to take them on physically up front and our driving line-out and scrum caused them problems. Now we have to hope Harlequins can do us a favour in Toulouse this weekend.
"All we can do now is concentrate on winning in London next week. If we can do that then we're still in with a chance of going through into a European quarter-final.
"If it is the Heineken Cup, then great. If it is the Amlin Challenge Cup, then we will give that a good crack as well."
As the countdown continues for RWC2015, Tournament Chief Executive Debbie Jevans visited the Millennium Stadium to discuss preparations for the eight matches and reveal the positive news that 100,000 tickets for games at the home of Welsh rugby have sold in the last seven days.
Jason Harries is targeting a first win on the World Series circuit this season with Wales. The series returns to action this weekend in Dubai where Harries is part of a team hoping to build from its efforts in round one in October.
Wales skipper Jevon Groves says his side have addressed a few points from Gold Coast and aim to 'hit the ground running' in the next two rounds of the World Series, kicking off with this weekend in Dubai before heading off to South Africa next week.
Wales Sevens manager Steff Thomas is hopeful his side can build from a quarter-final spot in the opening round of the World Series in Australia when his side take part in the forthcoming double header in Dubai and South Africa.