Newport skipper Andrew Coombs has impressed Dragons head coach Paul Turner.
Following strong performances against Connacht, Toby Faletau and Andrew Coombs have been retained their places for Saturday's derby clash against the Ospreys.
"We are well aware of the need to keep building for the future and this season we have tried to blood a few of our youngsters," Dragons head coach Paul Turner.
"Andrew's selection came off the back of some outstanding performances for Newport both in terms of his playing and his leadership and Toby has shown maturity in the way he has played for us this season. Their involvement in tonight's game is testament to the confidence we have in their abilities.
"We were obviously all disappointed with the result in Connacht last week but there were clear weaknesses in our performance which cost us the game.
"Despite that, I can't fault the effort the players put in, although at this level, putting in 100% effort is not enough if you can't keep the errors out of the game. We'll be focussed on ball retention and being clinical - two of the main failings with our performance last week.
"The Ospreys are one of Europe's on-form teams at the moment. Although they may have players out, the same was said of Munster before they came here and even with several internationals unavailable they were still able to boast a very strong side and the Ospreys will be the same. We need to be at our best to beat them."
Backs Martyn Thomas, Richard Fussell, Aled Brew, Will Harries, Matthew Watkins, Ashley Smith, Tom Riley, James Arlidge, Jason Tovey, James Leadbeater Wayne Evans.
Forwards Hugh Gustafson, Ben Castle, Pat Palmer, Tom Willis (Capt), Steve Jones, Rob Sidoli, Hoani Macdonald, Luke Charteris, Grant Webb, Danny Lydiate, Toby Faletau, Andrew Coombs, Gavin Thomas.
Sam Cross and Luke Treharne have been named as co-captains of the Wales Sevens side as head coach Gareth Williams names his 12-man squad to play in the first leg of the HSBC World Series in Dubai next weekend.
Bedwas head coach Steve Law and players Nicky Griffiths and Alun Rees extol the virtues of the close knit club as they prepare to host third place RGC 1404 - who are one place head of them on the Principality Premiership points table - on Saturday.
Many of the Wales squad have said Diolch (thank you) to someone who played an important part in their early playing days by nominating them to be invited to the Wales v South Africa match. One person, Gowerton Comprehensive geography teacher Mr Dean Mason was nominated by two of his former pupils, Dan Biggar and Sam Davies.
The second WRU disability rugby pilot has been delivered, this time in Caerphilly schools, culminating in a festival at the Caerphilly Centre of Sporting Excellence, Ystrad Mynach tomorrow. Plans are in place to set up a Disability Rugby Club in Newbridge to provide long-term playing opportunities.
WRU TV: Hear from inside the Wales camp as Neil Jenkins discusses this weekend's clash with South Africa and how the squad are looking to put in a strong performance to round of the 2016 Under Armour Series