NIck Mallett's preparations for the meeting with Wales have been disrupted by three late injuries enforcing changes to the starting linuep.
Centre Andrea Masi has been ruled out from tomorrow's game in Cardiff after suffering lower back pain this morning.
The Racing Metro Paris player will be replaced in the Azzurri starting line-up by Gonzalo Canale, while Matteo Pratichetti will be on the bench.
Masi's retirement comes on the back of Mallett losing two forwards yesterday. Lock Carlo Del Fava and flanker Paul Derbyshire have been ruled out the Italy starting line-up for the clash against Wales in the Millennium Stadium.
Both forwards suffered muscular injuries during Thursday's training session. Gloucester's lock Marco Bortolami and MPS Viadana's flanker Josh Sole will replace them in the Azzurri starting line-up while lock Valerio Bernabò and flanker.Manoa Vosaeai have been called-up by head-coach Nick Mallett as bench replacements.
Sam Cross and Luke Treharne have been named as co-captains of the Wales Sevens side as head coach Gareth Williams names his 12-man squad to play in the first leg of the HSBC World Series in Dubai next weekend.
Bedwas head coach Steve Law and players Nicky Griffiths and Alun Rees extol the virtues of the close knit club as they prepare to host third place RGC 1404 - who are one place head of them on the Principality Premiership points table - on Saturday.
Many of the Wales squad have said Diolch (thank you) to someone who played an important part in their early playing days by nominating them to be invited to the Wales v South Africa match. One person, Gowerton Comprehensive geography teacher Mr Dean Mason was nominated by two of his former pupils, Dan Biggar and Sam Davies.
The second WRU disability rugby pilot has been delivered, this time in Caerphilly schools, culminating in a festival at the Caerphilly Centre of Sporting Excellence, Ystrad Mynach tomorrow. Plans are in place to set up a Disability Rugby Club in Newbridge to provide long-term playing opportunities.
WRU TV: Hear from inside the Wales camp as Neil Jenkins discusses this weekend's clash with South Africa and how the squad are looking to put in a strong performance to round of the 2016 Under Armour Series