A late penalty by USA fly half Kimber Rozier proved the difference as Wales fell to a 7-10 defeat in their 2014 World Cup warm-up match at Pandy Park in Cross Keys.
Both sides scored one converted try apiece with winger Vanesha McGee ploughing over for USA and No 8 Sioned Harries replying in the second half for Wales.
Both sides ignored the wind and rain to play an open game of rugby with McGee and full back Akilaini Baravilala a constant threat with ball in hand for USA while Dyddgu Hywel and Laurie Harries featured regularly in counter attacks for Wales.
The teams were deadlocked until the 39th minute when USA ran the ball right and McGee dived over to score a well-executed try despite the best efforts of Harries and Hywel in defence. Rozier landed an excellent conversion to give the Americans a hard fought 7-0 lead at the interval.
Wales got back in to the game in the early stages of the second half through their forwards with Caryl Thomas and Catrin Edwards willing workhorses.
Wales got back on level terms in the 60th minute after holding onto possession for several phases. The ball was spread wide where Sioned Harries was lurking with intent and the speedy No 8 showed a clean pair of heels as she cut back against the grain to score under the posts. Laurie Harries added the extras to bring the scores level at 7-7.
Wales continued to attack but were guilty of coughing up possession at crucial times. USA made them pay by bursting downfield to set up Rozier for a penalty after Welsh forwards were penalised for coming in at the side of a ruck. The fly half had no trouble striking the ball between the uprights to edge her side back in front.
Wales finished the match in the ascendency but couldn't find a way through as USA held out for a gritty win.
Despite the narrow defeat, Wales Women's head coach Rhys Edwards was satisfied with his team's efforts.
"Going into the game we didn't know much about them but we knew it was going to be a tough game, especially as they are ranked in the top five teams of the world. The scoreboard doesn't really reflect that so I'm pretty pleased with the performance.
"We created some chances against one of the best teams in the world - the difference being when they get a chance they score, we don't. We take two, three, four or five times to get on the score board. We've got to show some composure and a bit of belief but we are certainly knocking on the door.
"We are improving and we showed that today. As we look ahead to the World Cup, we have another game against Ireland and there is no reason why we can't kick on from there and challenge in France."
Head coach Rowland Phillips and key front rower Carys Phillips look ahead to games against Spain and Ireland as Wales Women ramp up their preparations for the forthcoming Six Nations. The two warm-up games are a 'massive opportunity to refine the squad' according to the Welsh camp.
Martyn Phillips has discussed details of the newly published 'Strategy for Welsh Rugby' which puts in black and white terms the plans and direction of the governing body of the national sport in Wales for the next decade.
WRU chief executive Martyn Phillips has urged Welsh rugby fans to follow in the footsteps of their soccer counterparts at last summer's Euro Championship by backing their team to the hilt in the upcoming RBS 6 Nations campaign.
Chief executive Martyn Phillips has highlighted the plans for Wales to become a breeding ground for national and elite club rugby coaches, which are contained in the WRU's 10-year 'Strategy for Welsh Rugby'.
Andrew Coombs is enjoying his new role as Nelson forwards coach. The former Dragons and Wales lock has big ambitions to become a professional coach but feels it's important to learn the ropes in grassroots rugby and where better than his home club Nelson, with friends and family close to hand.
Students at Brynllywarch Hall School, near Newtown, have transformed their own lives, and are now having a positive impact on others through rugby. The sport has had a life-changing effect on the well-being of the students who are now delivering rugby sessions to local primary schools and playing for a new mixed ability side
Wales reached their first semi-final since 2013 in the opening round of this season's HSBC World Rugby Sevens Series in Dubai. WRU TV's Graeme Gillespie recaps on what proved to be an eventful tournament
Wales and Ospreys back row James King, who came through the North Wales age grade system, nominated North Wales Regional Community Rugby Manager Marc Roberts, in the WRU's 'Diolch' initiative where squad players thanked those who played a part in their rise to the top.
Beating Merthyr has boosted Carmarthen Quins hopes of reaching a top eight spot in the Principality Premiership. Quins captain Haydn Pugh is delighted with his team's progress and is determined that everyone from the Under 6s through to the senior team, enjoys the ride.
When the Wales squad were asked to nominate individuals who played a big part in their early playing days, Wales and Dragons full back and wing Hallam Amos thought of his former Monmouth School rugby coach John Bevan.
Sam Cross and Luke Treharne have been named as co-captains of the Wales Sevens side as head coach Gareth Williams names his 12-man squad to play in the first leg of the HSBC World Series in Dubai next weekend.
Bedwas head coach Steve Law and players Nicky Griffiths and Alun Rees extol the virtues of the close knit club as they prepare to host third place RGC 1404 - who are one place head of them on the Principality Premiership points table - on Saturday.
Many of the Wales squad have said Diolch (thank you) to someone who played an important part in their early playing days by nominating them to be invited to the Wales v South Africa match. One person, Gowerton Comprehensive geography teacher Mr Dean Mason was nominated by two of his former pupils, Dan Biggar and Sam Davies.
The second WRU disability rugby pilot has been delivered, this time in Caerphilly schools, culminating in a festival at the Caerphilly Centre of Sporting Excellence, Ystrad Mynach tomorrow. Plans are in place to set up a Disability Rugby Club in Newbridge to provide long-term playing opportunities.