Running out at RFU HQ will be a stark contrast to his involvement last time around when his memories of that glorious night come from the stands and the pub rather than the pitch.
"I may well have been in Walkabout, Cardiff! My mates are passionate Welsh fans as well, so we went to Walkabout and it's amazing how much support the boys have. To see everyone jumping around and singing - it was brilliant," said Webb.
"I know what it's like for the fans and it would be good to do well for them. They pay good money and support us everywhere we go, so it would be good to pay them back. It would be great to see a lot of Wales fans travelling to Twickenham to support the boys.
"The only time I've been there was with Wales Sevens. It was a half-empty ground, nothing like it will be this weekend. England have been playing well and are a great side who will be confident, so the atmosphere inside the ground will be electric."
Wales versus England fixtures have always held a special place in the sporting psyche of Welshmen and women around the globe and Webb is no different. Memories of the historic Scott Gibbs inspired success in London at the turn of the Millennium still loom large for the 25-year-old and he can't wait to try and play his part in a 2014 repeat at Twickenham.
"When I was growing up, everyone would talk about the big battles between Wales and England. Those are the matches you want to be involved in, the heated battles," added Webb.
"I came across them with Wales U16s and U18s. They were a very big side then, but we had a strong team as well with the likes of Warby (Sam Warburton) and Jon Davies. They were always good, even matches - and I think we won both games.
"My earliest memory of Wales-England games was when Scott Gibbs went over to score that winning try at Wembley. He did something special because we hadn't beaten them for a while. Everyone speaks about that score and whatever else happens in these matches because Wales and England are rivals. You think about those things - players who have scored winning tries - and you hope one day it will be you."