Ireland beat Wales by two points last season at Aberavon.
Ireland Women Head Coach Philip Doyle has made two changes to the side that demolished Scotland at Ashbourne last Friday night for the forthcoming clash against Wales.
Niamh Briggs is named at full-back and Larissa Muldoon comes in at scrum-half. The two players making way, Jackie Shiels and Amy Davis, are named among the replacements.
Hat-trick hero Sophie Spence will again line out alongside Marie Louise Reilly in the second row and Ireland will be hoping that Lynne Cantwell and Alison Miller who both scored a brace of tries against the Scots can have a similar impact against the Welsh. Fiona Coghlan will captain the side and Ashleigh Baxter comes onto the bench in place of Orla Fitzsimons.
Doyle commented, "The performance we put in against Scotland was coming for sometime but we are under no illusions as to the challenge the Welsh girls will present.
"There was only two points between the teams last year so this week we will require a further step up in performance from the group.
Sam Cross and Luke Treharne have been named as co-captains of the Wales Sevens side as head coach Gareth Williams names his 12-man squad to play in the first leg of the HSBC World Series in Dubai next weekend.
Bedwas head coach Steve Law and players Nicky Griffiths and Alun Rees extol the virtues of the close knit club as they prepare to host third place RGC 1404 - who are one place head of them on the Principality Premiership points table - on Saturday.
Many of the Wales squad have said Diolch (thank you) to someone who played an important part in their early playing days by nominating them to be invited to the Wales v South Africa match. One person, Gowerton Comprehensive geography teacher Mr Dean Mason was nominated by two of his former pupils, Dan Biggar and Sam Davies.
The second WRU disability rugby pilot has been delivered, this time in Caerphilly schools, culminating in a festival at the Caerphilly Centre of Sporting Excellence, Ystrad Mynach tomorrow. Plans are in place to set up a Disability Rugby Club in Newbridge to provide long-term playing opportunities.
WRU TV: Hear from inside the Wales camp as Neil Jenkins discusses this weekend's clash with South Africa and how the squad are looking to put in a strong performance to round of the 2016 Under Armour Series