Charteris has been out of action since December 2012
Luke Charteris could make his long-awaited return to top-class action in Perpignan's Heineken Cup opener with Gloucester on Saturday.
The Wales second-row underwent knee surgery after rupturing ligaments in December 2012.
He was set to make his comeback against Biarritz Olympique in the Top14 on the weekend but made 40-minute cameo appearance for the Catalan club's development side instead.
Charteris suffered no ill-affects from the injury and is now in line to be unleashed upon the Cherry & White's as Europe's premier club competition gets underway.
Perpignan have been drawn in Pool Six, alongside Edinburgh, Gloucester and Munster
Charteris won the first of his 40 Wales caps in 2004 and has been an ever-present feature of their squad in recent years.
But he has not pulled on the Three Feathers since facing Australia just weeks before his injury struck.
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