Charteris has been out of action since December 2012
Luke Charteris could make his long-awaited return to top-class action in Perpignan's Heineken Cup opener with Gloucester on Saturday.
The Wales second-row underwent knee surgery after rupturing ligaments in December 2012.
He was set to make his comeback against Biarritz Olympique in the Top14 on the weekend but made 40-minute cameo appearance for the Catalan club's development side instead.
Charteris suffered no ill-affects from the injury and is now in line to be unleashed upon the Cherry & White's as Europe's premier club competition gets underway.
Perpignan have been drawn in Pool Six, alongside Edinburgh, Gloucester and Munster
Charteris won the first of his 40 Wales caps in 2004 and has been an ever-present feature of their squad in recent years.
But he has not pulled on the Three Feathers since facing Australia just weeks before his injury struck.
UEFA has today confirmed the Football Association of Wales (FAW) has been successful in its bid for the Millennium Stadium to host the 2017 UEFA Champions League Final on Saturday 3rd June, 2017 (kick-off: 19.45hrs GMT).
The winners of a filmmaking competition organised by the education charity Into Film and the WRU enjoyed a behind the scenes tour of the Millennium Stadium - and a chance to be photographed with the WRU's fire-breathing, rugby loving mascot, Scorch The Dragon, and Welsh international, Jake Ball.
The Wales Under 20 camp are in a quietly confident mood as they face Ireland in the U20 Championship, with Coaching Co-Ordinator Allan Lewis and full back Dafydd Howells targeting a top five finish in the tournament.
Wales U20 may start as favourites against Japan this evening in the U20 Championship, but Team Manager Mark Taylor is warning against complacency. He is also hoping a good win will boost morale and 'kickstart' performances.
Coach Richard Hodges is hoping Wales U20 can put a disappointing campaign behind them when they tackle Japan tomorrow as they look to finish the U20 Championship strongly to secure a good seeding for next year's tournament.