The likes of Adam Thomas and Jason Harries are taking part in the tournament, just a couple of Wales Sevens players who are likely to be on show.
"I'm really looking forward to it. Any chance you get to play sevens is great and especially playing with the Welsh Students, it's always fun," said captain and aspiring doctor Luke Treharne.
"I've been playing sevens for about three or four years now so I've been playing on the Great Britain circuit.
"And I've just got back from playing with Great Britain Students out in Kazan in Russia so I've played quite a bit of this form of the game recently."
Last season saw the Wales Students side beat Germany in Heidelberg before a narrow defeat to England Students in Bristol.
And with seven Welsh students helping Great Britain Students to a bronze medal at the recent World University Games in Russia, the team will be hoping to continue from that success.
"Welsh students played a key role in Great Britain's success in Kazan recently and we're hoping we can transfer that success into the Foster's Sevens tournament," said Wales Students team manager Adrian Evans.
"We face Carmarthen Quins who are obviously a regular Premiership side and have a number of Wales Sevens men in their squad.
"But we'll be going all out to test them with ball in hand and see what happens."
Evans added: "One of the main roles of Wales Students is to bring players through for Wales Sevens.
"Sam Cross is a good example having played for the students for the last two years as well as representing Wales under Paul John.
"The majority of last year's students have now moved on to play for Premiership clubs so we're bringing players through.
"That's something we want to carry on."
Treharne, who played alongside George North at the Scarlets Academy before moving on to study medicine, said: "I'd like to consider myself more of a sevens player than a 15 a side player.
"Obviously every team will want to progress as far as possible but we'll hope to get past our first game and then see how far we can go.
"Hopefully we can do well and I can continue to play as much Sevens as I can throughout the year."
Tickets for the Foster's National Sevens are on sale now at just £10 for adults, £5 for Under 16s and £20 for a family ticket (2 adults, 2 children). Go to wru.co.uk/nationalsevens to purchase tickets or call 0844 8471881 (Ticketmaster) or 02920 230130 (Ticketline). Personal callers can also purchase tickets from the WRU shop, 8 Westgate Street or from Ticketline, 47 Westgate Street.