With 10 of their starting side starting their first game at the Millennium Stadium though, there is an argument to say England's inexperience may be to Wales' advantage.
But while he denies this to be the case, the English skipper knows what his side are in for when they step out just before 5pm.
"People always talk about the Millennium Stadium as one of the best stadiums to go out there and perform rugby in," he said.
"It's my first time on the pitch, I think I came here when I was about 15 to watch a Wales versus Barbarians game but I think there were only about 30,000 people there.
"People always rate this stadium as one of the best in the world so we're under no illusions as to how loud it's going to be."
Forwards coach Graham Rowntree added: "Playing in the Millennium, I've done it on several occasions and it's a cracking atmosphere.
"Ultimately this young group of players have to deal with these challenges, that's why I used to play the game."
Owen Farrell, Robshaw himself and hooker Tom Youngs are just three of the 10 players who have never played at the Millennium Stadium. But Robshaw says the experience of coaches like Rowntree will be a huge help as he prepares for his biggest game as captain.
"There are 10 players new to the scene but we've got a great set of coaches who have been here whether it's playing or coaching and we have to be fully prepared," added the Harlequins man.
"We've spoken about what to expect so we don't have any surprises. It is an incredible stadium and people say it's a noisy atmosphere but we have to be composed and do our thing.
"Obviously the crowd are going to be extremely passionate, both English and Welsh fans, but we want to go out there and put on a good show."
You can follow every minute of the action between Wales and England at www.wru.co.uk/live just prior to kick-off.