Following a run from the bench last week James Davies returns to the starting line up with Joe Griffin moving from full back to fly half to replace James Thomas.
In the pack Ryan Harford comes back into the front row with James Murphy moving back to the second row following last weeks run at flanker. Dan Crimmins returns at No8. Lewis Smout will be looking to get on the field from the replacements bench in order to win his club cap for 20 games this season.
The clash will be the first time the two sides have met since Mark Ring left The Keys to take up the backs coach position with the Blue and Blacks back in November.
The Keys are keeping in touch at the top of the league and currently lie in third place while Cardiff are sitting in mid-table in seventh place winning six of their 14 games so far with a total of 30 points.
At Pandy Park back in October and with Ring still with the black and whites, Keys ran out winners in an entertaining clash by 20-13.
Last season at the Arms Park The Keys won well by 32-24 so a similar win could potentially see Keys climb to second place.
Cardiff 15. Jamie Davies 14. Ifan Evans 13. Max Woodward 12. Darren Ryan 11 Shaun Powell (c) 10 Joe Griffin 9. Garyn Lucas; 1 Campese Ma'afu 2 Aaron Fowler 3 Ryan Harford 4 James Murphy 5 Matthew Screech 6 Nick White 7 Ben Roach 8 Dan Crimmins
Replacements: 16 Lewis Smout 17 Jac Hopkins 18 Ethan Lewis 19 Dan Partridge 20 Rhys Luckwell 21 Sion Hopkins 22 Matt Smith 22 Will Thomas
Cross Keys 15. Gareth David 14. Kristian Baller 13. Luke Ford 12. Aled James 11. Nathan Trowbridge 10. Dorian Jones 9. Rhys Dyer (c); 1. Richard Cornock 2. Ben Parry 3. Anthony Lott 4. Tom Lampard 5. Ollie Hodge 6. Rhys Peebles 7. Scott Matthews 8. Adam Powell
Replacements: Dan Watchurst, Rhys Miller, Craig Gould, Danny Hodge, Rob Nash, Ryan James, Phil Williams, Nathan Williams.