Talismanic Italy skipper Sergio Parisse will miss Saturday's showdown against Wales after being suspended for 30 days.
Parisse will be free to play again on 18 March, after seeing red last weekend playing for his club Stade Francais against Bordeaux-Begles when he was dismissed for allegedly insulting match referee Laurent Cardona.
The ban, 40 days with 10 suspeneded, rules him out of Italy's remaining RBS 6 Nations games this season against Wales, England and Ireland.
The No 8 was sent off after 36 minutes of Stade's home match with Bordeaux-Begles, having scored a try in the fourth minute.
Italy coach Jacques Brunel had already called veteran flanker Mauro Bergamasco into his squad to face Wales.
WRU International Skills Coach Jason Strange is a busy man, combining the new role with that of Wales Under 20 attack coach, Ebbw Vale head coach and continuing to teach at Ebbw Fawr Learning Community.
Warren Gatland and Sam Warburton look ahead to this week's crunch RBS 6 Nations tie against France, where the Wales skipper in particular is keen to make his mark, as Paris has proved a bleak place for him in the past.
Following their historic win over England, Wales Under 20 suffered a narrow, 36-34 loss to their Scottish counterparts last weekend, despite outscoring them by five tries to three. Watch the match highlights and reaction.
WRU TV go behind the scenes with the Wales squad as they put the final touches in place ahead of the clash against Scotland at Murrayfield. Follow the squad on their captain's run, the kickers visit to Murrayfield and Neil Jenkins' press conference