Paddy Power, Official Betting Supplier to the WRU, make Wales the slight favourites to claim victory in Cardiff. The Welsh are 4/6 to win the match and 10/11 to win with a handicap of -2 points.
The generous bookmaker is also offering one of his world famous Money-Back Specials on the match. If a forward scores the first try of the match, Paddy Power will refund all losing Tryscorer bets. As an extra bonus, the same offer is being run in the England v Scotland and Italy v France matches.
It was a testing Dove Men Series campaign for Wales but with renewed focus, it would be no surprise to see their form pick up. The return of talismanic prop Adam Jones should also go a long way to boosting the Welsh chances.
Recent history looks very good for Wales. They've won three games on the bounce against Ireland and since 2007, have amassed a record of four wins and two defeats from six games against Saturday's opponents. It's a particularly impressive turnaround considering the ascendency Ireland had established prior to this. From 1995 up to the start of the Warren Gatland era, Wales had won four and lost 10 of their games with Ireland.
With that sort of recent form, you'd fancy the hosts to cover a -2 point handicap and even a -5 point handicap at 13/10 is very tempting. Games between the nations have generally been close with little to separate the teams. In four of the last five games, there has been less than a converted try between the teams at the final whistle. With that in mind, backing Wales to win by 1-5 points at 4/1 or 6-10 points at 4/1 could be the way to go. You can cover both of those bases by backing Wales to win by 1-10 at 8/5 on the Alternative Winning Margin betting.
As ever, Wales are packed full of attacking threat, but his excellent record against Ireland makes Jonathan Davies stand out as the pick for the First Tryscorer betting. The centre has scored three tries in three appearances against Ireland. He's 14/1 to be First Tryscorer in Saturday's game and 7/2 to score a try at any time. Interestingly, he's 18/1 to score two or more tries which is tempting considering his brace against Ireland almost exactly one year ago.