Ashley Beck has been ruled out for six to eight weeks.
Wales and the Ospreys have been dealt a blow after Ashley Beck was ruled out for up to two months.
The centre suffered an ankle injury during his try-scoring cameo against Newport Gwent Dragons on New Year's Eve.
And following further investigation it has been discovered that the 22-year-old has suffered significant ligament damage.
He will subsequently miss the Ospreys crucial Heineken Cup matches with Leicester Tigers and Benetton Treviso and at least the first three fixtures of the RBS 6 Nations, against Ireland, France and Italy.
"Ashley suffered a significant ligament injury to his ankle during the New Year's Eve fixture at Rodney Parade," said Ospreys head of physio.
"We've conducted investigations over the course of the last week to determine the full extent of the ligament damage and plan his rehabilitation effectively.
"Based on the advice received, we are currently treating this as a 6-8 week injury so would expect to see him back in action by the end of February."
Jamie Roberts and Jon Davies remain the tried and tested combination in the Welsh midfield, while the likes of Scott Williams and James Hook offer further options.
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Wales winger Luke Morgan has established himself as one of the deadliest finishers on the Sevens World Series. WRU TV's Graeme Gillespie catches up with him on the eve of this weekend's round in Glasgow.
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WRU Chief Executive Roger Lewis, Deputy Minister for Culture, Sport and Tourism Ken Skates and WRU Chairman Gareth Davies earlier this week launched a new competition in conjunction with the WRU unveiling its archive room.
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Ystradgynlais and Ynysddu played out a titanic struggle at Taffs Well in the SSE SWALEC Bowl semi-final. At the end of the game neither team could be separated after a 15-15 stalemate but Ystradgynlais go through on try count.
Blues strike first in JD III battle - Newport Gwent Dragons lock Andrew Coombs, WRU referee Dylan Llyr Jones and Cardiff Blues hooker Matthew Rees decide dressing room allocations for Judgement Day III
Wales Under 18 captain Calum Haggett has received a conditional offer to read Biomedical Science at St Anne's College, Oxford. WRU chairman Gareth Davies went to meet Calum and Coleg y Cymoedd Principal Judith Evans to wish him luck in his exams and pass on some of his personal experience.