Ashley Beck has been ruled out for six to eight weeks.
Wales and the Ospreys have been dealt a blow after Ashley Beck was ruled out for up to two months.
The centre suffered an ankle injury during his try-scoring cameo against Newport Gwent Dragons on New Year's Eve.
And following further investigation it has been discovered that the 22-year-old has suffered significant ligament damage.
He will subsequently miss the Ospreys crucial Heineken Cup matches with Leicester Tigers and Benetton Treviso and at least the first three fixtures of the RBS 6 Nations, against Ireland, France and Italy.
"Ashley suffered a significant ligament injury to his ankle during the New Year's Eve fixture at Rodney Parade," said Ospreys head of physio.
"We've conducted investigations over the course of the last week to determine the full extent of the ligament damage and plan his rehabilitation effectively.
"Based on the advice received, we are currently treating this as a 6-8 week injury so would expect to see him back in action by the end of February."
Jamie Roberts and Jon Davies remain the tried and tested combination in the Welsh midfield, while the likes of Scott Williams and James Hook offer further options.
The Welsh Rugby Union is forming a new Youth Board with a brief to help keep more young people involved in the game during their late teenage years and beyond. The first task of the fifteen strong Board will be to analyse and consider the issues which lead to a number of youngsters drifting away from the sport between the ages of 16 and 21. To apply visit www.wru.wales/youthboard
The Foster's Challenge Cup will involve the 12 Principality Premiership sides and will run during European and British & Irish Cup weeks, providing vital fixtures for the participating clubs and an opportunity for upcoming players to step up to semi-professional rugby and make a claim for starting places within the Premiership squads.
Eighty schools and colleges in Wales now have a full time rugby officer as part of the WRU's school club hub scheme. All of the school club hub officers recently gathered at the National Centre of Excellence for various workshops.
With Liam Williams forced out of the World Cup through injury, lock Luke Charteris and Skills Coach Neil Jenkins say they have to put yesterday's defeat behind them as Wales now look ahead to another physical encounter against South Africa in the quarter-finals of the Rugby World Cup.
WRU Consultant Head of Physical Performance Paul Stridgeon praises the Physical Performance department for their work and dedication as he addresses the media ahead of Wales' Pool A clash against Australia
Twelve young people have been selected to follow a one year WRU Coach Core apprenticeship programme. Coach Core was set up by the Royal Foundation of the Duke and Duchess of Cambridge and Prince Harry as part of the Olympics legacy in 2012 and the Duke of Cambridge was on hand to meet the apprentices on their first day in the job. The programme has been funded by the Hunter Foundation.
The WRU has launched a campaign to create a long term legacy for Welsh club rugby by highlighting the advantages of volunteering. Rhian Edwards, a volunteer at Seven Sisters, has enjoyed many benefits of her volunteering at a grassroots rugby club including being part of the Rugby World Cup volunteer workforce after being nominated by the WRU - and the WRU is asking for more people to develop their 'Welsh rugby roots'.