Cardiff Blues have been dealt a blow after Jamie Roberts was sidelined for up to six weeks.
The Wales star suffered a hyperextension of his elbow in last weekend's agonising 14-12 defeat to Australia.
He saw a specialist yesterday and is expected to be out of action for up to six weeks.
The powerful centre heads an alarming injury list for the Blues, who are also without Leigh Halfpenny and Bradley Davies.
Halfpenny is recovering from a severe stinger and continues to be assesses and Davies is expected to return to training next week following severe concussion.
Michael Patterson, Dan Fish, Andi Kyriacou and Tom James are also recent additions to the treatment room and are likely to miss the back-to-back clashes with Montpellier.
Blues director of rugby Phil Davies admits the injuries are frustrating but he has urged his fringe players to step up and prove a point.
"Only a fortnight ago things were looking very positive for us, when we were welcoming back some key players," said Davies.
'However, we have been extremely unfortunate to pick up a raft of injuries in the last few weeks.
"It is frustrating that we cannot select from a full strength squad for these crucial matches, but on a positive note, it gives a chance for some of our other players to step up and show what they can do.
"Montpellier has a formidable reputation in the French league as a very physical team with an extremely strong set-piece.
"Their scrum is particularly strong this season, having won all 17 of their put-ins so far in both Heineken Cup games and their six lineout steals is a joint high this season.
"These are areas in which we will have to be at our best if we are to compete this Sunday."
The Half a Game initiative is currently sweeping across Wales and proving a major success. The scheme aims to give every young player at least half a game every weekend. WRU TV recently visited a festival in Narberth where clubs have fully embraced the initiative.
Both Bargoed and Swansea were seeking their first win of the Principality Premiership season this afternoon. It proved a fruitful day for the hosts - not only did they win, but Bargoed claimed a try bonus point.
Cardiff managed to keep their unbeaten record at home intact, but only just as Bridgend made them work extremely hard before the Blue and Blacks secured a hard fought Principality Premiership win at the BT Sport Arms Park last night.
Former Wales back row Andy Powell gives a guided tour of The Wern, home of Merthyr RFC, who are determined to prove a lot of people wrong and make their mark in their first season in the Principality Premiership.
Wales Sevens head coach Gareth Williams looks back on the Rio Sevens success where he helped GB win silver. He believes the successful campaign is a huge boost to his Welsh squad as they prepare for another World Series, as WRU TV's Graeme Gillespie discovers
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Llandovery made it three in a row when they defeated Aberavon in the final of the National Foster's 7s at BT Sport Cardiff Arms Park on Sunday. On another eventful day of sevens, Newport claimed the Plate and the Dragons won the women's crown
Last week saw Cardiff welcome players from around the world for the 21st Golden Oldies Festival. The tournament features players over 35 years of age, and this year's event saw a select few represent the WRU in a 'friendly' against the Wooden Spoon.
Wales Under 18 captain Callum Bradbury is delighted to have seen his side claim a narrow 18-17 victory against a strong SA Schools 'A' side to end the three-match Under 19 International Series in South Africa on a high note.
The Wales U18 squad spent an emotional day in the drug-riddled townnship of Hout Bay. Hout Bay Warriors President Fred Johannes said the visit was 'the talk of the town' and will dream about the day everyday for the rest of his life.
RGC 1404's new head coach Mark Jones is hoping to build 'something special' in north Wales and is already looking forward to the development region participating in the Principality Premiership for the very first time.