Cardiff Blues have been dealt a blow after Jamie Roberts was sidelined for up to six weeks.
The Wales star suffered a hyperextension of his elbow in last weekend's agonising 14-12 defeat to Australia.
He saw a specialist yesterday and is expected to be out of action for up to six weeks.
The powerful centre heads an alarming injury list for the Blues, who are also without Leigh Halfpenny and Bradley Davies.
Halfpenny is recovering from a severe stinger and continues to be assesses and Davies is expected to return to training next week following severe concussion.
Michael Patterson, Dan Fish, Andi Kyriacou and Tom James are also recent additions to the treatment room and are likely to miss the back-to-back clashes with Montpellier.
Blues director of rugby Phil Davies admits the injuries are frustrating but he has urged his fringe players to step up and prove a point.
"Only a fortnight ago things were looking very positive for us, when we were welcoming back some key players," said Davies.
'However, we have been extremely unfortunate to pick up a raft of injuries in the last few weeks.
"It is frustrating that we cannot select from a full strength squad for these crucial matches, but on a positive note, it gives a chance for some of our other players to step up and show what they can do.
"Montpellier has a formidable reputation in the French league as a very physical team with an extremely strong set-piece.
"Their scrum is particularly strong this season, having won all 17 of their put-ins so far in both Heineken Cup games and their six lineout steals is a joint high this season.
"These are areas in which we will have to be at our best if we are to compete this Sunday."
Wales Head Coach Rob Howley talks to WRU TV's Sebastian Barrett about the 36-man squad he has just named for the forthcoming Under Armour series, which includes two uncapped players, Ospreys duo Sam Davies and Rory Thornton.
Head coach Rowland Phillips is deligthed he can now call BT Sport Cardiff Arms Park home for his Wales Women's side, who launch their international season next month with games against Scotland and UK Armed Forces in the heart of the capital city.
Wales Sevens star Sam Cross has put his home town club of Brynmawr on the map after winning a silver medal at the Rio Olympics with Team GB. His club have now honoured him by naming their players bar after him, as WRU TV discovered at the official launch, recently.
One of the newest members of the Principality Premiership, Bargoed admit it's proving to be a steep learning curve at the highest level, but are determined to become a force to be reckoned with. WRU TV visited the club last weekend when they took on Llanelli.
Table-topping Aberavon travel to north Wales to tackle RGC 1404 as both teams defend unbeaten starts to the season in the Principality Premiership. WRU TV's Graeme Gillespie visited the Wizards to see how their preparations were going for the game of the weekend.
The Half a Game initiative is currently sweeping across Wales and proving a major success. The scheme aims to give every young player at least half a game every weekend. WRU TV recently visited a festival in Narberth where clubs have fully embraced the initiative.
Both Bargoed and Swansea were seeking their first win of the Principality Premiership season this afternoon. It proved a fruitful day for the hosts - not only did they win, but Bargoed claimed a try bonus point.
Cardiff managed to keep their unbeaten record at home intact, but only just as Bridgend made them work extremely hard before the Blue and Blacks secured a hard fought Principality Premiership win at the BT Sport Arms Park last night.
Former Wales back row Andy Powell gives a guided tour of The Wern, home of Merthyr RFC, who are determined to prove a lot of people wrong and make their mark in their first season in the Principality Premiership.
Wales Sevens head coach Gareth Williams looks back on the Rio Sevens success where he helped GB win silver. He believes the successful campaign is a huge boost to his Welsh squad as they prepare for another World Series, as WRU TV's Graeme Gillespie discovers