Cross Keys travel West to take on Carmarthen Quins at the Parc on Saturday.
Greg Woods makes a total of six changes to the starting line-up from the side that started last week's home defeat to Bedwas.
Leon Andrews returns from injury and Richard Cornock has completed a suspension as Keys look to bounce back from three consecutive defeats against the inform Quins.
Carmarthen may have won four and lost four of their eight league games so far this season but they have enjoyed an impressive recent run, demolishing Swansea 41-17 in their league encounter last weekend.
Jason Harries bagged a hat-trick as the Quins' backs ran riot. Alex Pickersgill, Darren Daniel and Lee Williams added further scores whilst Jack Maynard kicked four conversions and a penalty.
With the injury situation slowly improving for Keys, they will be looking to bounce back and repeat last season's victory over the Quins.
Carmarthen captain Ian Jones returns from injury while Rhys Thomas is also back in contention.
Cross Keys: 15 Gareth David 14 Nathan Williams13 Leon Andrews 12 Luke Ford 11 Nathan Trowbridge 10 Dorian Jones 9 Rhys Dyer, 1 Richard Cornock 2 Garry Horrigan 3 Marc Jones 4 Danny Hodge 5 Tom Lampard 6 Rhys Peebles 7 Rob Nash (c) 8 Adam Powell. Replacements: Sean Higgins, Anthony Lott, James Johnstone, Jamie Sollis, Scott Matthews, Ryan James, Elliot Jones, Nathan, Luke Williams.
Meet the members of the WRU's inaugural Youth Board - after an online selection process which saw a host of high calibre candidates submit video applications the WRU has made its first 15 appointments.The board is made up of individuals aged between 16 and 21, and will meet for the first time at Principality Stadium on Monday 15th February.
The Wales Women's team headed to Dare Valley Country Park on a team bonding exercise as the entire squad got together for the very first time in preparation for this season's Six Nations championship which kicks off on Saturday with a clash against defending champions Ireland, in Donnybrook.
Wales Head Coach Warren Gatland discusses his team selection for the opening round of the RBS 6 Nations where he leads his side against Ireland, on Sunday. As WRU TV's Luke Brodley discovers, Gatland is fully aware of the challenges the defending champions pose
WRUTV caught up with Wales Women captain Rachel Taylor at the RBS 6 Nations launch and how a good crowd really helps boost the girls performance. Tickets for all three Women's home games at The Gnoll, Neath are available from www.wru.wales/tickets