Having registered home wins over Ystrad Rhondda and Llantrisant in the previous two warm up games, Ponty will now step up a significant level in preparation for the competitive season to come.
Against fellow Premiership opposition, Ponty have named a strong starting line up with the remainder of the squad available to appear from an extended replacements' bench which will include full back Adam Thomas and flankers Ed Siggery and Rhys Shellard..
Outside half Simon Humberstone makes his comeback from a recent knee operation, with centre Gavin Dacey also coming in for a first pre-season start. Promising youngsters Geraint Walsh, Owen Jenkins and Tom Pascoe are given another opportunity to impress at full back, wing and centre respectively.
Craig Locke has recovered from a calf strain to pack down beside club skipper Chris Dicomidis in the second row.
Langmead underlined the significance of the Llandovery clash in naming the squad.
"This will be a big step up for us in our pre-season build up and will be as close to an all-out league encounter as can be had," he said.
"Llandovery were a form team in the Premiership last season, pushing all the way for honours and to meet them on their own patch this early will be a big call for us.
"We have players jostling for selection in every position, and this game is another opportunity for them to impress."
Pontypridd: 15 Geraint Walsh 14 Owen Jenkins 13 Gavin Dacey 12 Tom Pascoe 11 Owen Williams 10 Simon Humberstone 9 Carl Thomas; 1Scott Roberts 2 Huw Dowden 3 Pat Palmer 4 Craig Locke 5 Chris Dicomidis (c) 6 Jake Thomas 7 Wayne O'Connor 8 Dan Godfrey