Waleswill play Argentina on November 10 (KO 2.30pm), Samoa on Friday November 16 (KO 7.30pm), New Zealand on November 24 (KO 5.15pm) and Australia on December 1 (KO 2.30pm).
The autumn series is now a massive attraction for rugby fans in Wales as the fixtures regularly attract top class international opposition.
WRU Group Chief Executive, Roger Lewis, said: "I am delighted we are able to announce such an excellent series of games for this autumn. Warren Gatland has always said we will only get better by playing the best and this autumn we have certainly met his challenge and lived up to his expectations.
"New Zealand are worthy world champions while facing Australia will be a prelude to the next summer's British and Irish Lions tour so those games are absolutely compelling.
"Argentina are great crowd favourites and tough opposition wherever they play and whoever they face while Samoa are quite literally one of the most powerful rugby teams around.
"Our current Welsh team plays a brand of compelling and engaging rugby which delights our fans and I am confident the series we have on offer will prove to be a great attraction."
Supporters can now pre-register their interest for tickets via the WRU website to ensure being first in the queue when the first tranche go on public sale at the end of April.
Welsh rugby clubs are now being asked to place their orders while members of the public are being urged to get in touch with their local club to see if any are available for sale.
Tickets are then likely to go on general public sale early in May when any member of the public will be able to buy them through the usual official channels.
Ticket prices are:
Argentina£40, £30, and £10 for juniors (under 16).
Samoa£25, and £10 for juniors (under 16)
New Zealand£80, £75, £50 and £30.
Australia£70, £60, £40 and £20.