Tickets for the mouthwatering encounter have gone on sale to the public today (MONDAY) at £25 for adults and £10 for juniors under the age of 16.
This year the Barbarians game will take place shortly before Wales set off for their summer Test match tour of Australia.
Wales will be wary of the opposition which is renowned for attracting some of the legends of the global game.
In the 2011 encounter the Italian No 8 Sergio Parisse earned the Man of the Match award after a typically barnstorming display.
He was the latest in a string of legendary players to create rugby history in the black and white Barbarians jersey.
In 2011 the encounter was to commemorate the 130th anniversary of the formation of the Welsh Rugby Union.
The June home fixture for Wales is now becoming a staple of the Wales rugby sporting calendar with a growing following of supporters enticed by the prospect of summer rugby in the capital.
The Barbarians is a representative team without an official home ground and since their first game in 1890 they have played around the world.
The Baa-Baa's have even notched up some notable victories including wins against the likes of South Africa and New Zealand.
For the 2012 encounter against Wales the Barbarians are again expected to attract a star studded line-up set to thrill the crowd.
The Barbarians have now played against Wales eight times notching up six wins and losing twice.
Tickets for the game can be purchased via the WRU website or by calling the hotline on 0844 777 888. To watch Wales train at the Millennium Stadium this Wednesday, free of charge, vist