Joe Bedford is among four players set to make their Dragons debut against Munster.
New signings Tom Brown, Rhys Buckley, Nathan Williams and Joe Bedford are set to make their Dragons RaboDirect PRO12 debuts on Saturday at Musgrave Park as the Men of Gwent take on reigning champions Munster (KO 7:45pm)
Scrum half Wayne Evans has returned from a shoulder injury picked up in the pre-season friendly against Russia to take a place in the squad and Martyn Thomas returns after recovering from the second of two broken legs which have kept him out of league action for several months.
Lewis Evans (calf) and Jamie Smith (back) are being rested for the match.
"Both Lewis and Jamie are ok but we don't want to play anyone who isn't 100% fit," said Dragons Head Coach Darren Edwards.
"There's a great deal of competition in the squad and I'm confident that players who have been given an opportunity this weekend will put in strong performances."
Dragons squad for Munster
Backs Martyn Thomas, Steffan Jones, Adam Hughes, Mike Poole, Pat Leach, Tom Riley, Ashley Smith, Jason Tovey, Wayne Evans, Joe Bedford, Forwards Phil Price, Tom Willis (c), Rhys Buckley, Nathan Williams, Dan Way, Ben Castle, Adam Jones, Jevon Groves, Robert Sidoli, Andrew Coombs, Gavin Thomas, Hugo Ellis, Tom Brown
Twelve young people have been selected to follow a one year WRU Coach Core apprenticeship programme. Coach Core was set up by the Royal Foundation of the Duke and Duchess of Cambridge and Prince Harry as part of the Olympics legacy in 2012 and the Duke of Cambridge was on hand to meet the apprentices on their first day in the job. The programme has been funded by the Hunter Foundation.
The WRU has launched a campaign to create a long term legacy for Welsh club rugby by highlighting the advantages of volunteering. Rhian Edwards, a volunteer at Seven Sisters, has enjoyed many benefits of her volunteering at a grassroots rugby club including being part of the Rugby World Cup volunteer workforce after being nominated by the WRU - and the WRU is asking for more people to develop their 'Welsh rugby roots'.
Wales head coach Warren Gatland and captain Sam Warburton say their first prioirty on Sunday in the opening game of the World Cup is to win against Uruguay and not get overly concerned with points difference.
With only days to go until the biggest rugby competition in the world begins, rugby fans visiting Cardiff this autumn will be able to enjoy a special display at National Museum Cardiff as part of the celebrations surrounding the Rugby World Cup.