The stakes are high for Paul Turner's side as, with three league matches remaining, they seem set to face an awkward play-off with the team that finishes third in the Italian championship.
The Dragon must win their remaining three matches and hope the Ospreys remain winless for the remainder of the season if they are to overhaul the 10 point advantage enjoyed by Lyn Jones's side. And Turner knows his side have to fight for every point in Dublin and in the following two Magners League fixtures next week.
"It will be a tough challenge against the form side in the Magners League this weekend yet, as the squad reflects, we are looking to prepare for the next three league fixtures as best we can.
"The players are aware that I'm asking for a huge performance on the weekend, as I will be in all three fixtures over the seven days."
Dragons squad: Kevin Morgan, Gareth Wyatt, Richard Mustoe, Richard Fussell, Paul Emerick, Gareth Maule, Phillip Dollman, Ceri Sweeney, Jason Tovey, Andy Williams, Wayne Evans, Adam Black, Ben Daly, Steve Jones, Lee Harrison, Rhys Thomas, Adam Jones, Peter Sidoli, Andy Hall, Jamie Ringer, Richard Parks, James Harris, Michael Owen, Lewis Evans