Blues Coach Dai Young names an unchanged line-up for the massive away test against the three-time Heineken Cup champions. The Welsh region travel to the south of France in confident mood after a convincing 20-0 away win in Edinburgh last weekend.
Young said: "It will be a massive hurdle for us but one we're all looking forward to. We've have to raise our standards because of who we're playing against. Toulouse haven't got their standing in the Heineken Cup by chance, they've earned it.
"We know that on any given day they can put teams to the sword. We've got to go over there and throw caution to the wind and try to express ourselves."
Centre Gareth Thomas returns to his former club while Wales Grand Slam heroes Tom Shanklin, Martyn Williams and Gethin Jenkins are all involved.
Blues: Ben Blair; Jamie Roberts, Tom Shanklin, Gareth Thomas, Tom James; Dai Flanagan, Jason Spice; Gethin Jenkins, Gareth Williams, Taufa'ao Filise, Deiniol Jones, Paul Tito, Maama Molitika, Xavier Rush (Capt), Martyn Williams
Replacements: John Yapp, T Rhys Thomas, Scott Morgan, Ben White, Richie Rees, Nicky Robinson, Jamie Robinson