Ceiron Thomas, Jonathan Davies, Iestyn Thomas, Matthew Rees and Vernon Cooper are all included as Davies freshens up his pack. Phil John, Mahonri Schwalger and Morgan Stoddart drop to the bench while Simon Easterby returns on the replacements bench from a knee complaint.
Scarlets Head Coach Davies said: "There's nothing happening we didn't know about. We're trying hard to produce a platform and we can achieve that.
"But in our last match against Leinster you have to hold your hand up and say we were beaten by a better side. It's now a case of pushing forward, aiming for the highest possible finish in the league and preparing for next season."
Scarlets: Ceiron Thomas; Dafydd James, Regan King, Jonathan Davies, Mark Jones; Stephen Jones, Dwayne Peel (Capt); Iestyn Thomas, Matthew Rees, Bruce Douglas, Vernon Cooper, Scott MacLeod, Dafydd Jones, Alix Popham, Gavin Thomas
Replacements: Phil John, Mahonri Schwalger, Nathan Thomas, Simon Easterby, Gavin Cattle, Rhys Priestland, Morgan Stoddart