Rob Higgitt, Sililo Martens, Kees Meeuws, Simon Maling and David Lyons will all start new coach Nigel Davies's first match in charge in Belfast.
Wales internationals Morgan Stoddart, Mark Jones, Stephen Jones and Matthew Rees also feature in a strong line-up for Friday's clahs at Ravenhill.
And Scarlets captain Simon Easterby reckons the players are in the right frame of mind to get their campaign off to a flyer.
Flanker Easterby said: "Nigel is single minded and the players have responded in pre-season training.
"He has built a coaching team around him, with Paul Moriarty joined by John Muggleton.
"Brad Harrington and Ryan Campbell have come in on the conditioning side to complement what Nigel wants to do."
Scarlets: Morgan Stoddart, Darren Daniel, Rob Higgitt, Gavin Evans, Mark Jones, Stephen Jones, Sililo Martens; Iestyn Thomas, Matthew Rees, Kees Meeuws, Lou Reed, Simon Maling, Simon Easterby (c), David Lyons, Gavin Thomas
Replacements from: Deacon Manu, Mahonri Schwalger, Vernon Cooper, Dafydd Jones, Martin Roberts, Ceiron Thomas, Nathan Brew, Daniel Evans, Scott MacLeod






