Xavier Rush has been named on the Cardiff Blues bench for the clash with Connacht.
Talismanic number eight Rush suffered a shoulder injury in pre-season and was expected to be out until at least next month.
And while Rush is back ahead of schedule, there is also returns from injury for Richie Rees and Deiniol Jones.
The Blues have made a stuttering start in the Magners League but coach Dai Young insists they are determined to bounce back from last week's 28-20 defeat at Munster.
Young said: "That was probably the best we've played all season. If we play like that week-in, week-out we'll win a lot more than we lose.
"All we can do now is build on the performance at Musgrave Park for the visit of Connacht to the Arms Park."
Wales prop Gethin Jenkins misses out with a neck injury and joins Tom James, Martyn Williams, Rhys Williams and Sam Warburton on the sidelines.
The Blues will defend an unbeaten record at the Arms Park which stretches back to January while Connacht have not won in Cardiff since 2001.
Blues: Leigh Halfpenny; Richard Mustoe, Jamie Robinson, Jamie Roberts, Gareth Thomas; Ceri Sweeney, Jason Spice; John Yapp, T Rhys Thomas, Gary Powell, Deiniol Jones, Paul Tito (capt), Maama Molitika, Andy Powell, Robin Sowden-Taylor.
Replacements: Taufa'ao Filise, Rhys Williams, Scott Morgan, Xavier Rush, Richie Rees, Nicky Robinson, Tom Shanklin.
Connacht: F Carr; A Wynne, J Hearty, M Deane, M Roberts; A Dunne, F Murphy; J Lyne, A Flavin, R Morris; A Browne, M Swift; J Muldoon (C), J O'Connor, C Rigney.
Replacements: S Cronin, R Loughney, A Farley, M McCarthy, K Campbell, I Keatley, L Bibo.
With just a week to go before Wales kick off their Rugby Women's World Cup campaign against hosts France in Paris, head coach Rhys Edwards and flanker Sioned Harries are looking ahead to the tournament with optimism.
After two years in the international wilderness, Adi Taviner is hoping to make up for lost time when she takes part in her second Women's Rugby World Cup which kicks off in Paris next Friday where Wales take on hosts, France.
The WRU's Women and Girls legacy events - #TRY OUR GAME have proved popular this week with current players and newcomers to the game learning new skills and picking up tips from national squad players.
We caught up with Shona and Ellie from the Wales women team ahead of the start of the Women's Rugby World Cup in Paris next month at a recent women's training session to encourage and promote more women and girls to try their hand at rugby. #tryourgame
The Women's Rugby World Cup warm-up clash between Wales and USA proved bittersweet for centre Elen Evans. Despite being one of the star performers on the day on her 50th Test appearance, USA edged home 10-7 at Cross Keys.
Wales completed their Junior World Championship campaign with a victory over Samoa. Team manager Mark Taylor and No 8 James Benjamin reflect on a tournament which saw Wales win three games and lose two.