Xavier Rush has been named on the Cardiff Blues bench for the clash with Connacht.
Talismanic number eight Rush suffered a shoulder injury in pre-season and was expected to be out until at least next month.
And while Rush is back ahead of schedule, there is also returns from injury for Richie Rees and Deiniol Jones.
The Blues have made a stuttering start in the Magners League but coach Dai Young insists they are determined to bounce back from last week's 28-20 defeat at Munster.
Young said: "That was probably the best we've played all season. If we play like that week-in, week-out we'll win a lot more than we lose.
"All we can do now is build on the performance at Musgrave Park for the visit of Connacht to the Arms Park."
Wales prop Gethin Jenkins misses out with a neck injury and joins Tom James, Martyn Williams, Rhys Williams and Sam Warburton on the sidelines.
The Blues will defend an unbeaten record at the Arms Park which stretches back to January while Connacht have not won in Cardiff since 2001.
Blues: Leigh Halfpenny; Richard Mustoe, Jamie Robinson, Jamie Roberts, Gareth Thomas; Ceri Sweeney, Jason Spice; John Yapp, T Rhys Thomas, Gary Powell, Deiniol Jones, Paul Tito (capt), Maama Molitika, Andy Powell, Robin Sowden-Taylor.
Replacements: Taufa'ao Filise, Rhys Williams, Scott Morgan, Xavier Rush, Richie Rees, Nicky Robinson, Tom Shanklin.
Connacht: F Carr; A Wynne, J Hearty, M Deane, M Roberts; A Dunne, F Murphy; J Lyne, A Flavin, R Morris; A Browne, M Swift; J Muldoon (C), J O'Connor, C Rigney.
Replacements: S Cronin, R Loughney, A Farley, M McCarthy, K Campbell, I Keatley, L Bibo.
Twelve young people have been selected to follow a one year WRU Coach Core apprenticeship programme. Coach Core was set up by the Royal Foundation of the Duke and Duchess of Cambridge and Prince Harry as part of the Olympics legacy in 2012 and the Duke of Cambridge was on hand to meet the apprentices on their first day in the job. The programme has been funded by the Hunter Foundation.
The WRU has launched a campaign to create a long term legacy for Welsh club rugby by highlighting the advantages of volunteering. Rhian Edwards, a volunteer at Seven Sisters, has enjoyed many benefits of her volunteering at a grassroots rugby club including being part of the Rugby World Cup volunteer workforce after being nominated by the WRU - and the WRU is asking for more people to develop their 'Welsh rugby roots'.
Wales head coach Warren Gatland and captain Sam Warburton say their first prioirty on Sunday in the opening game of the World Cup is to win against Uruguay and not get overly concerned with points difference.
With only days to go until the biggest rugby competition in the world begins, rugby fans visiting Cardiff this autumn will be able to enjoy a special display at National Museum Cardiff as part of the celebrations surrounding the Rugby World Cup.