Home spun Cardiff Blues player Dai Flanagan pitched in with a conversion and penalty to complete the scoring and Neath were sunk. The visitors' points came from a first-half penalty from Matthew Jarvis and a second half try from replacement wing David Evans.
For the second weekend in a row Swansea had the cup of victory snatched from their lips at the death as they were beaten 22-21 at Cross Keys. Paul Smithson was the architect of the All Whites' latest agonizing failure as he converted a try from Julian Price and kicked five penalties - the last one to win the game with the game's final action.
Tries from John Lewis and Tim Evans were at the heart of Swansea's score, but they weren't enough to avoid another defeat to follow their 29-27 reverse against Aberavon the previous weekend.
Prolific Aberavon outside half Jamie Davies went through the 3,000 points barrier for the Wizards as he helped himself to 16 points in a convincing 31-9 home triumph over Llandovery.
The former Wales Youth No 10 landed four penalties and converted two of the home side's three tires - from No 8 Richard Morris, wing Richard Carter and a penalty try.
Llanelli hit Premiership new boys Pontypool for six at Pontypool Park as they ran in half-a-dozen tries, all of which Scarlets outside half Rhys Priestland converted, in a 42-26 win.
Wing Matthew Jacobs notched a hat-trick and props Ian Jones and Aled Hopkins also got in on the act. There were three tries for the home side, who once again showed they have the ability to compete at this level, from Dan Robinson, Rhys Bowen and Geraint O'Driscoll.
Newport notched victory number 156 in their amazing 415 match series against arch-rivals Cardiff as they triumphed 30-3 at Rodney Parade. Cardiff have yet to win a Premiership game in Newport and never looked like troubling the competent and confident home side.
Wing Mike Poole led the home charge with two tries and Jason Tovey and Andrew Borwn ensured the bonus point. Wales Under 20 cap Tovey also landed a penalty and there were two conversions and a drop goal from Dan Griffiths.
Glamorgan Wanderers withstood a ferocious second half fight-back from Bedwas to hold out for a 29-28 away win. The Wanderers led 22-9 at the break, yet 'lost' the second half 19-7.
The visitors ensured a try bonus with four touchdowns in that first period and they added another after the break - Neil Aiono, Jason Pocock, Dafydd Hewitt, Scott Snedden and James Loxton socred the tries.
But Bedwas came storming back in the second half and almost did enough to take the points. In the end, though, they had to settle for a single bonus point with tries from Adam Hughes (2) and Jimmy Norris, two conversions and three penalties.
Wales prop Adam Jones played 78 minutes for Bridgend as the Ravens maintained their good start with a 33-19 home win over Ebbw Vale. Two tries from Grant Epton and 18 points from Gareth David made up the bulk of their scoring and their fourth try from Gareth Bowen capped off a fine afternoon's work with a bonus point.