Cardiff Blues coach Dai Young has rung the changes for his side's trip to the Liberty Stadium to face the Ospreys on Tuesday night (kick-off 7.35pm).
Having drawn 16-16 with the Magners League champions Leinster on the opening day of the season, the Blues now find themselves facing the EDF Energy Cup holders three days later.
And with Ulster coming to the Arms park on Friday night, making it three games in seven days, Young has stood down a number of first-choice players for the away trip.
"The Blues v Ospreys is obviously a big game in Wales, so it's a pity it's shoved in the middle of the week. We've only really had one day preparation for it which isn't ideal," explained Young.
"We've had to juggle teams because when you go from a Saturday game to a Tuesday match, the preparation is practically non existent.
"They have the same coaches who were there last year with Lyn, so we're expecting very much more of the same. Maybe they will make little changes here and there, but we know enough about their players and they know enough about us."
"I think both teams have a lot of skilful players, so I have no doubt that it will be a quality game. The Liberty Stadium is a great stadium to play at and I think the Ospreys are going to be up there at the end of the season.
"I know its going to be a big test for us."
There are nine new faces among the starting XV from the side that faced Leinster, with seven players, including new club skipper Paul Tito, reverting to bench duty. Welsh international Robin Sowden-Taylor returns to action for the first time since damaging his shoulder in March.
Cardiff Blues: Ben Blair; Richard Mustoe, Jamie Robinson, Jamie Roberts, Aled Brew; Ceri Sweeney, Darren Allinson; Taufa'ao Filise, T. Rhys Thomas, Gary Powell, Bradley Davies, Scott Morgan, Ben White, Robin Sowden-Taylor, Andy Powell.
Relacements: Gethin Jenkins, Gareth Williams, Paul Tito, Ma'ama Molitika, Jason Spice, Nicky Robinson, Tom Shanklin
The Wales Women's team headed to Dare Valley Country Park on a team bonding exercise as the entire squad got together for the very first time in preparation for this season's Six Nations championship which kicks off on Saturday with a clash against defending champions Ireland, in Donnybrook.
Wales Head Coach Warren Gatland discusses his team selection for the opening round of the RBS 6 Nations where he leads his side against Ireland, on Sunday. As WRU TV's Luke Brodley discovers, Gatland is fully aware of the challenges the defending champions pose
WRUTV caught up with Wales Women captain Rachel Taylor at the RBS 6 Nations launch and how a good crowd really helps boost the girls performance. Tickets for all three Women's home games at The Gnoll, Neath are available from www.wru.wales/tickets
The WRU Coach Core Apprenticeship scheme is developing young people who are already benefitting Welsh rugby while improving their own career prospects. WRU TV caught up with some of the individuals who are making a difference.
The Wales Sevens squad had some spare time to kill while waiting for a training session in Dubai, so decided to play: Let's head a football into a rubbish bin. It seemed such a simple idea at the time....