Cardiff Blues coach Dai Young has rung the changes for his side's trip to the Liberty Stadium to face the Ospreys on Tuesday night (kick-off 7.35pm).
Having drawn 16-16 with the Magners League champions Leinster on the opening day of the season, the Blues now find themselves facing the EDF Energy Cup holders three days later.
And with Ulster coming to the Arms park on Friday night, making it three games in seven days, Young has stood down a number of first-choice players for the away trip.
"The Blues v Ospreys is obviously a big game in Wales, so it's a pity it's shoved in the middle of the week. We've only really had one day preparation for it which isn't ideal," explained Young.
"We've had to juggle teams because when you go from a Saturday game to a Tuesday match, the preparation is practically non existent.
"They have the same coaches who were there last year with Lyn, so we're expecting very much more of the same. Maybe they will make little changes here and there, but we know enough about their players and they know enough about us."
"I think both teams have a lot of skilful players, so I have no doubt that it will be a quality game. The Liberty Stadium is a great stadium to play at and I think the Ospreys are going to be up there at the end of the season.
"I know its going to be a big test for us."
There are nine new faces among the starting XV from the side that faced Leinster, with seven players, including new club skipper Paul Tito, reverting to bench duty. Welsh international Robin Sowden-Taylor returns to action for the first time since damaging his shoulder in March.
Cardiff Blues: Ben Blair; Richard Mustoe, Jamie Robinson, Jamie Roberts, Aled Brew; Ceri Sweeney, Darren Allinson; Taufa'ao Filise, T. Rhys Thomas, Gary Powell, Bradley Davies, Scott Morgan, Ben White, Robin Sowden-Taylor, Andy Powell.
Relacements: Gethin Jenkins, Gareth Williams, Paul Tito, Ma'ama Molitika, Jason Spice, Nicky Robinson, Tom Shanklin
As the countdown continues for RWC2015, Tournament Chief Executive Debbie Jevans visited the Millennium Stadium to discuss preparations for the eight matches and reveal the positive news that 100,000 tickets for games at the home of Welsh rugby have sold in the last seven days.
Jason Harries is targeting a first win on the World Series circuit this season with Wales. The series returns to action this weekend in Dubai where Harries is part of a team hoping to build from its efforts in round one in October.
Wales skipper Jevon Groves says his side have addressed a few points from Gold Coast and aim to 'hit the ground running' in the next two rounds of the World Series, kicking off with this weekend in Dubai before heading off to South Africa next week.
Wales Sevens manager Steff Thomas is hopeful his side can build from a quarter-final spot in the opening round of the World Series in Australia when his side take part in the forthcoming double header in Dubai and South Africa.