Cardiff Blues coach Dai Young has rung the changes for his side's trip to the Liberty Stadium to face the Ospreys on Tuesday night (kick-off 7.35pm).
Having drawn 16-16 with the Magners League champions Leinster on the opening day of the season, the Blues now find themselves facing the EDF Energy Cup holders three days later.
And with Ulster coming to the Arms park on Friday night, making it three games in seven days, Young has stood down a number of first-choice players for the away trip.
"The Blues v Ospreys is obviously a big game in Wales, so it's a pity it's shoved in the middle of the week. We've only really had one day preparation for it which isn't ideal," explained Young.
"We've had to juggle teams because when you go from a Saturday game to a Tuesday match, the preparation is practically non existent.
"They have the same coaches who were there last year with Lyn, so we're expecting very much more of the same. Maybe they will make little changes here and there, but we know enough about their players and they know enough about us."
"I think both teams have a lot of skilful players, so I have no doubt that it will be a quality game. The Liberty Stadium is a great stadium to play at and I think the Ospreys are going to be up there at the end of the season.
"I know its going to be a big test for us."
There are nine new faces among the starting XV from the side that faced Leinster, with seven players, including new club skipper Paul Tito, reverting to bench duty. Welsh international Robin Sowden-Taylor returns to action for the first time since damaging his shoulder in March.
Cardiff Blues: Ben Blair; Richard Mustoe, Jamie Robinson, Jamie Roberts, Aled Brew; Ceri Sweeney, Darren Allinson; Taufa'ao Filise, T. Rhys Thomas, Gary Powell, Bradley Davies, Scott Morgan, Ben White, Robin Sowden-Taylor, Andy Powell.
Relacements: Gethin Jenkins, Gareth Williams, Paul Tito, Ma'ama Molitika, Jason Spice, Nicky Robinson, Tom Shanklin
Welsh players and management joined Deputy Minister for Sport Ken Skates at the Pierhead Building, Cardiff Bay earlier this week to reveal the Union's pioneering school-club hub initiative has been so successful the project will now almost double the scale of the original project.
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Blues strike first in JD III battle - Newport Gwent Dragons lock Andrew Coombs, WRU referee Dylan Llyr Jones and Cardiff Blues hooker Matthew Rees decide dressing room allocations for Judgement Day III
Wales Under 18 captain Calum Haggett has received a conditional offer to read Biomedical Science at St Anne's College, Oxford. WRU chairman Gareth Davies went to meet Calum and Coleg y Cymoedd Principal Judith Evans to wish him luck in his exams and pass on some of his personal experience.
Dodgy tattoos, carthorses, Avatar and soft chins are revealed by Wales Sevens players Tom Williams and Sam Cross as they profile the Wales Sevens squad taking part in Hong Kong this weekend in the latest round of the HSBC Sevens World Series.