Richard Hodges is taking no chances with the cup challenge of Carmarthen Athletic by packing the side with his most experienced players.
Mark Roper starts at outside half with Jason Pocock coming in at fullback.
In the pack Matthew Bolton starts at prop, Nick Kelly resumes as captain in the second row and Richard Thomas and Mike Grimes both start.
The one survivor of the last time the two sides met is Mark O'Leary who is amongst the substitutes. The game also sees the return to the side of Lee Highgate who starts after an enforced layoff.
Glamorgan Wanderers: 15. Jason Pocock 14. Robin Lock 13. Ben Warbuton 12. James Thomas 11. Charlie Johnson 10. Mark Roper 9. Luke Evans; 1. Matthew Bolton 2. Ross Johnson 3. Scott Andrews 4. Nick Kelly (capt) 5. Tom Evans 6. Richard Thomas 7. Lee Highgate 8. Mike Grimes.
Replacements: 16. Richard Emms 17. Mark O'Leary 18. Ben Rose 19. Gareth Knight 20. Glenn Holloway 21. James Loxton 22. Steve Cullen
The annual Women's club launch was held at the Wales Centre of Excellence where National Women's Head Coach and Programme Lead Rhys Edwards, Competition Secretary Adrian Howell and Cardiff Met player Ffion Jones express eagerness for the new campaign to get under way.
WRU TV follows Wales' RWC training squad on day one of their camp in North Wales. The squad were greeted to an official welcome in Colwyn Bay and then headed for an afternoon of team building at ZipWorld