Prop Phil John replaces Iestyn Thomas (thumb) in the Scarlets side for the return clash against Ulster.
The Scarlets are down to the bare bones of a squad as Nigel Davies's side prepare to win their first game in Europe for the first time since March 2007.
The Scarlets, once proud flag bearers for the Welsh teams in Europe, haven't recorded a victory in the Heineken Cup in their last 10 games and face an Ulster side tomorrow night at Parc y Scarlets who are hoping to lay to rest their own bogey in the competition by recording a rare away victory.
With his squad already severely depleted, Davies has seen prop Iestyn Thomas forced out with a neck problem. His place will be taken by Phil John with young Aled Hopkins drafted in as cover from the ranks of Llanelli's Principality Premiership side.
Darren Daniel is one of two other changes. He replaces Ceiron Thomas on the right wing to make his 50th appearance for the Scarlets. Thomas drops down to the bench while Rhys Priestland replaces the injured Morgan Stoddart at full-back. Although a fly-half, Priestland is not entirely unfamiliar with the No15 shirt as he has played semi-pro rugby in that position.
After a lengthy spell on the sidelines, Scotland second row Scott MacLeod makes a welcome return to regional action and is named among the replacements.
Scarlets: R Priestland; D Daniel, R King, J Davies, M Jones; S Jones, M Roberts; P John, M Rees, D Manu, V Cooper, D Day, D Jones, S Easterby, D Lyons.
Replacements: K Owens, A Hopkins, S MacLeod, J Edwards, G Cattle, C Thomas, L Williams
Ulster Rugby: B Cunningham; A Trimble, D Cave, P Wallace, S Danielli; I Humphreys, I Boss; J Fitzpatrick, R Best [capt], B Botha, E O'Donoghue, R Caldwell, S Ferris, D Pollock, R Diack
Replacements: N Brady, T Court, M McCullough, K Dawson, P Marshall, P Steinmetz, C Schifcofske.
As the countdown continues for RWC2015, Tournament Chief Executive Debbie Jevans visited the Millennium Stadium to discuss preparations for the eight matches and reveal the positive news that 100,000 tickets for games at the home of Welsh rugby have sold in the last seven days.
Jason Harries is targeting a first win on the World Series circuit this season with Wales. The series returns to action this weekend in Dubai where Harries is part of a team hoping to build from its efforts in round one in October.
Wales skipper Jevon Groves says his side have addressed a few points from Gold Coast and aim to 'hit the ground running' in the next two rounds of the World Series, kicking off with this weekend in Dubai before heading off to South Africa next week.
Wales Sevens manager Steff Thomas is hopeful his side can build from a quarter-final spot in the opening round of the World Series in Australia when his side take part in the forthcoming double header in Dubai and South Africa.