Wanderers have been boosted with the presence of Blues players Ben white (above) and John Yapp (thumb).
Despite the success at St Helens last week, Glamorgan Wanderers coach Richard Hodges has made four changes to the starting line-up to face table topping Llanelli on Saturday.
In the back division Gareth Morris comes into the centre to replace Nick Gill who has a knee injury and Robin Lock and Charlie Johnson swap places in the squad.
Up front Scott Andrews returns in place of Mark O'Leary after being rested last week. He also takes over the captaincy due to the fact that Nick Kelly is injured. Kelly is replaced by Richard Thomas who moves from No.8. Mike Grimes who was on the bench last Saturday starts in the back row.
On the bench there is a strong Blues influence with John Yapp being joined by Jevon Groves and Ben White.
Glamorgan Wanderers: 15. James Loxton 14. Steve Cullen 13. Jamie Jones 12. Gareth Morris 11. Robin Lock 10. Scott Sneddon 9. Glen Holloway; 1. Nathan Trevett 2. Ryan Price 3. Scott Andrews (capt) 4. Richard Thomas 5. Gareth Knight 6. Nio Aiono 7. Ben Rose 8. Mike Grimes
Replacements: 16. Richard Emms 17. John Yapp 18. Ben White 19. Jevon Groves 20. Mark Roper 21. Luke Evans 22. Charlie Johnson
Wales and Ospreys back row James King, who came through the North Wales age grade system, nominated North Wales Regional Community Rugby Manager Marc Roberts, in the WRU's 'Diolch' initiative where squad players thanked those who played a part in their rise to the top.
Beating Merthyr has boosted Carmarthen Quins hopes of reaching a top eight spot in the Principality Premiership. Quins captain Haydn Pugh is delighted with his team's progress and is determined that everyone from the Under 6s through to the senior team, enjoys the ride.
When the Wales squad were asked to nominate individuals who played a big part in their early playing days, Wales and Dragons full back and wing Hallam Amos thought of his former Monmouth School rugby coach John Bevan.
Sam Cross and Luke Treharne have been named as co-captains of the Wales Sevens side as head coach Gareth Williams names his 12-man squad to play in the first leg of the HSBC World Series in Dubai next weekend.
Bedwas head coach Steve Law and players Nicky Griffiths and Alun Rees extol the virtues of the close knit club as they prepare to host third place RGC 1404 - who are one place head of them on the Principality Premiership points table - on Saturday.
Many of the Wales squad have said Diolch (thank you) to someone who played an important part in their early playing days by nominating them to be invited to the Wales v South Africa match. One person, Gowerton Comprehensive geography teacher Mr Dean Mason was nominated by two of his former pupils, Dan Biggar and Sam Davies.
The second WRU disability rugby pilot has been delivered, this time in Caerphilly schools, culminating in a festival at the Caerphilly Centre of Sporting Excellence, Ystrad Mynach tomorrow. Plans are in place to set up a Disability Rugby Club in Newbridge to provide long-term playing opportunities.
WRU TV: Hear from inside the Wales camp as Neil Jenkins discusses this weekend's clash with South Africa and how the squad are looking to put in a strong performance to round of the 2016 Under Armour Series