David Young has selected the Cardiff Blues side to face former Heineken Cup finalists Biarrtiz Olympique on Friday.
Wales internationals Leigh Halfpenny, Tom Shanklin, Andy Powell, Martyn Williams and Gethin Jenkins all return to the starting XV with Robin Sowden Taylor and Tom James on the bench.
Speaking ahead of the match David young said, "The Wales players are coming back battered, bruised and certainly mentally and physically drained. But they all desperately want to play in this game."
"They were a big part of our efforts prior to the internationals. They helped us get where we are now after a good start in the Heineken Cup."
Tickets for the match are selling fast with less than 200 stand tickets available. The Blues are advising supporters to purchase their tickets in good time ahead of the match, to avoid delay or disappointment on the night of the match.
Tickets for the match are available to purchase online at www.cardiffblues.com/tickets or by calling the ticket office on 029 2030 2030
Cardiff Blues: 15 Ben Blair 14 Leigh Halfpenny 13 Jamie Robinson 12 Tom Shanklin 11 Gareth Thomas 10 Nicky Robinson 9 Jason Spice 8 Andy Powell 7 Martyn Williams 6 Maama Molitka 5 Paul Tito 4 Deiniol Jones 3 Gary Powell 2 Gareth Williams 1 Gethin Jenkins
Replacements: 16 Taufa'au Filise 17 T Rhys Thomas 18 Scott Morgan 19 Robin Sowden Taylor 20 Darren Allinson 21 Ceri Sweeney 22 Tom James
Biarritz Olympique: 15 Marcelo Bosch 14 Takudzwa Ngwenya 13 Philippe Bidabe 12 Damien Traille 11 Ilikena Bolakoro 10 Julien Peyrelongue 9 Fabien Cibray 1 Fabien Barcella 2 Benjamin Noirot 3 Mosese Moala 4 Jérôme Thion 5 Trevor Hall 6 Peïo Som 7 Mohammed Dridi 8 Imanol Harinordoquy
Replacements: 16 Benoit August 17 Eduard Coetzee 18 César Damiani 19 Wenceslas Lauret 20 Romain Cabannes 21 Benjamin Thiery 22 Laurent Tranier
When the Wales squad were asked to nominate individuals who played a big part in their early playing days, Wales and Dragons full back and wing Hallam Amos thought of his former Monmouth School rugby coach John Bevan.
Sam Cross and Luke Treharne have been named as co-captains of the Wales Sevens side as head coach Gareth Williams names his 12-man squad to play in the first leg of the HSBC World Series in Dubai next weekend.
Bedwas head coach Steve Law and players Nicky Griffiths and Alun Rees extol the virtues of the close knit club as they prepare to host third place RGC 1404 - who are one place head of them on the Principality Premiership points table - on Saturday.
Many of the Wales squad have said Diolch (thank you) to someone who played an important part in their early playing days by nominating them to be invited to the Wales v South Africa match. One person, Gowerton Comprehensive geography teacher Mr Dean Mason was nominated by two of his former pupils, Dan Biggar and Sam Davies.
The second WRU disability rugby pilot has been delivered, this time in Caerphilly schools, culminating in a festival at the Caerphilly Centre of Sporting Excellence, Ystrad Mynach tomorrow. Plans are in place to set up a Disability Rugby Club in Newbridge to provide long-term playing opportunities.
WRU TV: Hear from inside the Wales camp as Neil Jenkins discusses this weekend's clash with South Africa and how the squad are looking to put in a strong performance to round of the 2016 Under Armour Series