Newbridge were the cup kings after they produced the biggest upset of the fourth round in the SWALEC Cup.
Joe Calzaghe's hometown club gave Bedwas a knockout blow by dumping out the top flight outfit in a 18-15 triumph at Bridge Field.
The Division One East leaders trailed by just two points at half-time after a brace of tries from Lenny Woodard cancelled out scores from Jimmy Norris and Deri Mattravers.
But the match was decided by centre John Hawker's try on the 55th minute, which was the only score of the second half.
Bedwas failed to recover and became the first and only Premiership team to depart the competition at the first hurdle.
There were routine wins for most of their Premiership counterparts, with Swansea picking up the biggest win of the fourth round, hammering Bala 104-3. Ospreys squad member Leigh Bevan crossed four times against the Division One North visitors.
Bridgend saw off local rivals Pencoed 37-6 at Brewery Field by running in six tries while Llandovery went one better in the 45-0 win at Beddau.
Welsh Premiership rivals Aberavon, Newport and Pontypridd also recorded comprehensive victories to ease into the fifth round.
But Pontypool were given a scare at Bonymaen before pulling through 13-5. Pooler went behind on ten minutes through a try from winger Robert Jones before first-half replies from Will Kershaw-Naylor and Calwyn Morgan gave the visitors a narrow 13-5 victory.
There was a dramatic finish in Llanelli, as Felinfoel led Caerphilly deep into injury-time. With the score tied at 31-31, having scored five tries to Caerphilly's four, the Carmarthenshire club looked to be heading through on the try count rule.
But Felinfoel lost their lineout with seconds remaining and outside-half Danny Ellis touched down under the posts to clinch victory for the visitors.
There was just time left for Ellis, a second-half supersub, to kick the conversion before the referee blew up to allow Caerphilly to go through 38-31.
Wales Head Coach Rob Howley talks to WRU TV's Sebastian Barrett about the 36-man squad he has just named for the forthcoming Under Armour series, which includes two uncapped players, Ospreys duo Sam Davies and Rory Thornton.
Head coach Rowland Phillips is deligthed he can now call BT Sport Cardiff Arms Park home for his Wales Women's side, who launch their international season next month with games against Scotland and UK Armed Forces in the heart of the capital city.
Wales Sevens star Sam Cross has put his home town club of Brynmawr on the map after winning a silver medal at the Rio Olympics with Team GB. His club have now honoured him by naming their players bar after him, as WRU TV discovered at the official launch, recently.
One of the newest members of the Principality Premiership, Bargoed admit it's proving to be a steep learning curve at the highest level, but are determined to become a force to be reckoned with. WRU TV visited the club last weekend when they took on Llanelli.
Table-topping Aberavon travel to north Wales to tackle RGC 1404 as both teams defend unbeaten starts to the season in the Principality Premiership. WRU TV's Graeme Gillespie visited the Wizards to see how their preparations were going for the game of the weekend.
The Half a Game initiative is currently sweeping across Wales and proving a major success. The scheme aims to give every young player at least half a game every weekend. WRU TV recently visited a festival in Narberth where clubs have fully embraced the initiative.
Both Bargoed and Swansea were seeking their first win of the Principality Premiership season this afternoon. It proved a fruitful day for the hosts - not only did they win, but Bargoed claimed a try bonus point.
Cardiff managed to keep their unbeaten record at home intact, but only just as Bridgend made them work extremely hard before the Blue and Blacks secured a hard fought Principality Premiership win at the BT Sport Arms Park last night.
Former Wales back row Andy Powell gives a guided tour of The Wern, home of Merthyr RFC, who are determined to prove a lot of people wrong and make their mark in their first season in the Principality Premiership.