Nigel Davies's Scarlets will be hoping to bounce back from opening defeats in the Heineken Cup.
The Scarlets have brought back their big guns for their trip to Ulster in a last ditch attempt to keep their European Cup hopes alive.
Nigel Davies's side are currently languishing in third place in Pool 4 after a home defeat to Harlequins and a hefty loss at Stade Francais. If the Scarlets stand any hope of making the knockout stages - and that's a faint one at best - they must gain maximum points at Ravenhill to kick start their campaign.
"Friday's game is a massive one for us. We're not where we want to be in Europe at this stage but I don't think it's completely over for us," explained Davies.
"If we can go to Belfast and get a result then that puts us in a position where we can look forward to two back-to-back home games.
"So, if we get a result in Belfast, then who knows? There's no doubt we've got to put in a big performance on Friday; we're a very proud team and we're not going to hide from putting in that performance. We'll fight all the way."
His squad includes four Wales players fresh from beating Australia at the Millennium Stadium - Dafydd Jones, Mark Jones, Stephen Jones and Matthew Rees. Also back in the fold is new Wales scrum-half Martin Roberts and Wales full-back Morgan Stoddart.
Davies said: "It's great to have them back. They've returned buoyed by last weekend's success and they're our most experienced, talented players so to have them all back in the group is brilliant. They've added a lot to everything we've done this week."
Scarlets long-term injuries include Kees Meeuws, Gavin Thomas and Rob Higgitt, with shorter-term difficulties for stars such as Gavin Evans, Simon Maling and Darren Daniel.
Scott MacLeod was not considered for this weekend as he works to overcome a recent long lay-off.
Davies said: "We've not got much fully fit cover behind the scrum at the moment but we've still been able to put out a very team."
Scarlets: 15 Morgan Stoddart. 14 Ceiron Thomas, 13 Regan King, 12 Jonathan Davies, 11 Mark Jones, 10 Stephen Jones, 9 Martin Roberts: 1 Iestyn Thomas, 2 Matthew Rees, 3 Deacon Manu, 4 Vernon Cooper, 5 Dominic Day, 6 Dafydd Jones, 7 Simon Easterby (capt), 8 David Lyons
Replacements - 16 Ken Owens, 17 Phil John, 18 Nathan Thomas, 19 Johnathan Edwards, 20 Gavin Cattle, 21 Rhys Priestland, 22 Lee Williams.
The Half a Game initiative is currently sweeping across Wales and proving a major success. The scheme aims to give every young player at least half a game every weekend. WRU TV recently visited a festival in Narberth where clubs have fully embraced the initiative.
Both Bargoed and Swansea were seeking their first win of the Principality Premiership season this afternoon. It proved a fruitful day for the hosts - not only did they win, but Bargoed claimed a try bonus point.
Cardiff managed to keep their unbeaten record at home intact, but only just as Bridgend made them work extremely hard before the Blue and Blacks secured a hard fought Principality Premiership win at the BT Sport Arms Park last night.
Former Wales back row Andy Powell gives a guided tour of The Wern, home of Merthyr RFC, who are determined to prove a lot of people wrong and make their mark in their first season in the Principality Premiership.
Wales Sevens head coach Gareth Williams looks back on the Rio Sevens success where he helped GB win silver. He believes the successful campaign is a huge boost to his Welsh squad as they prepare for another World Series, as WRU TV's Graeme Gillespie discovers
British and Irish Lions head coach Warren Gatland will be heading back home to take on the All Blacks next year where for him, success for 2017 is all about going to New Zealand and winning a Test Series.
Last week all roads led to Eugene Cross Park where defending champions Ebbw Vale hosted this season's launch of the Principality Premiership. WRU TV's Graeme Gillespie was there to capture the thoughts of Damien Hudd, captain of Ebbw Vale, and WRU Head of Performance, Geraint John.
Llandovery made it three in a row when they defeated Aberavon in the final of the National Foster's 7s at BT Sport Cardiff Arms Park on Sunday. On another eventful day of sevens, Newport claimed the Plate and the Dragons won the women's crown
Last week saw Cardiff welcome players from around the world for the 21st Golden Oldies Festival. The tournament features players over 35 years of age, and this year's event saw a select few represent the WRU in a 'friendly' against the Wooden Spoon.
Wales Under 18 captain Callum Bradbury is delighted to have seen his side claim a narrow 18-17 victory against a strong SA Schools 'A' side to end the three-match Under 19 International Series in South Africa on a high note.
The Wales U18 squad spent an emotional day in the drug-riddled townnship of Hout Bay. Hout Bay Warriors President Fred Johannes said the visit was 'the talk of the town' and will dream about the day everyday for the rest of his life.
RGC 1404's new head coach Mark Jones is hoping to build 'something special' in north Wales and is already looking forward to the development region participating in the Principality Premiership for the very first time.