Nigel Davies's Scarlets will be hoping to bounce back from opening defeats in the Heineken Cup.
The Scarlets have brought back their big guns for their trip to Ulster in a last ditch attempt to keep their European Cup hopes alive.
Nigel Davies's side are currently languishing in third place in Pool 4 after a home defeat to Harlequins and a hefty loss at Stade Francais. If the Scarlets stand any hope of making the knockout stages - and that's a faint one at best - they must gain maximum points at Ravenhill to kick start their campaign.
"Friday's game is a massive one for us. We're not where we want to be in Europe at this stage but I don't think it's completely over for us," explained Davies.
"If we can go to Belfast and get a result then that puts us in a position where we can look forward to two back-to-back home games.
"So, if we get a result in Belfast, then who knows? There's no doubt we've got to put in a big performance on Friday; we're a very proud team and we're not going to hide from putting in that performance. We'll fight all the way."
His squad includes four Wales players fresh from beating Australia at the Millennium Stadium - Dafydd Jones, Mark Jones, Stephen Jones and Matthew Rees. Also back in the fold is new Wales scrum-half Martin Roberts and Wales full-back Morgan Stoddart.
Davies said: "It's great to have them back. They've returned buoyed by last weekend's success and they're our most experienced, talented players so to have them all back in the group is brilliant. They've added a lot to everything we've done this week."
Scarlets long-term injuries include Kees Meeuws, Gavin Thomas and Rob Higgitt, with shorter-term difficulties for stars such as Gavin Evans, Simon Maling and Darren Daniel.
Scott MacLeod was not considered for this weekend as he works to overcome a recent long lay-off.
Davies said: "We've not got much fully fit cover behind the scrum at the moment but we've still been able to put out a very team."
Scarlets: 15 Morgan Stoddart. 14 Ceiron Thomas, 13 Regan King, 12 Jonathan Davies, 11 Mark Jones, 10 Stephen Jones, 9 Martin Roberts: 1 Iestyn Thomas, 2 Matthew Rees, 3 Deacon Manu, 4 Vernon Cooper, 5 Dominic Day, 6 Dafydd Jones, 7 Simon Easterby (capt), 8 David Lyons
Replacements - 16 Ken Owens, 17 Phil John, 18 Nathan Thomas, 19 Johnathan Edwards, 20 Gavin Cattle, 21 Rhys Priestland, 22 Lee Williams.
It was a double celebration for Wales and Ospreys scrum-half Rhys Webb when he called at the home of Welsh rugby to help commemorate the first anniversary of Principality Stadium and his return to fitness this weekend ahead of the RBS 6 Nations.
Prior to their departure to Wellington for the next leg of the World Series, Wales trained with England and Ireland. WRU TV caught up with Owen Jenkins who revealed the 'buzzword' which is driving the Wales squad on.
Wales head coach Rob Howley explains his decision to change the captaincy of the national side with Ospreys second row Alun Wyn Jones taking over from Sam Warburton for the forthcoming RBS 6 Nations. Howley is hoping his decision will allow Warburton to rediscover his 'mojo'.
How do you follow a dancing hippopotamus - the Ospreys wheelchair rugby team has just the 'oneness' to do it say the BBC! For a decade the sight of a herd of hippos synchronised swimming around their own private blue lagoon, has lit up our television screens at regular intervals between favourite BBC One shows. But now the nation's most watched channel has relinquished its famous amphibious mammals in favour of a new show-reel which includes the Ospreys wheelchair rugby team.
Head coach Rowland Phillips and key front rower Carys Phillips look ahead to games against Spain and Ireland as Wales Women ramp up their preparations for the forthcoming Six Nations. The two warm-up games are a 'massive opportunity to refine the squad' according to the Welsh camp.
Martyn Phillips has discussed details of the newly published 'Strategy for Welsh Rugby' which puts in black and white terms the plans and direction of the governing body of the national sport in Wales for the next decade.
WRU chief executive Martyn Phillips has urged Welsh rugby fans to follow in the footsteps of their soccer counterparts at last summer's Euro Championship by backing their team to the hilt in the upcoming RBS 6 Nations campaign.
Chief executive Martyn Phillips has highlighted the plans for Wales to become a breeding ground for national and elite club rugby coaches, which are contained in the WRU's 10-year 'Strategy for Welsh Rugby'.
Andrew Coombs is enjoying his new role as Nelson forwards coach. The former Dragons and Wales lock has big ambitions to become a professional coach but feels it's important to learn the ropes in grassroots rugby and where better than his home club Nelson, with friends and family close to hand.
Students at Brynllywarch Hall School, near Newtown, have transformed their own lives, and are now having a positive impact on others through rugby. The sport has had a life-changing effect on the well-being of the students who are now delivering rugby sessions to local primary schools and playing for a new mixed ability side
Wales reached their first semi-final since 2013 in the opening round of this season's HSBC World Rugby Sevens Series in Dubai. WRU TV's Graeme Gillespie recaps on what proved to be an eventful tournament
Wales and Ospreys back row James King, who came through the North Wales age grade system, nominated North Wales Regional Community Rugby Manager Marc Roberts, in the WRU's 'Diolch' initiative where squad players thanked those who played a part in their rise to the top.
Beating Merthyr has boosted Carmarthen Quins hopes of reaching a top eight spot in the Principality Premiership. Quins captain Haydn Pugh is delighted with his team's progress and is determined that everyone from the Under 6s through to the senior team, enjoys the ride.
When the Wales squad were asked to nominate individuals who played a big part in their early playing days, Wales and Dragons full back and wing Hallam Amos thought of his former Monmouth School rugby coach John Bevan.