Glamorgan Wanderers make one change in the backs and two up front for trip to Sardis Road.
Jason Pocock, after missing the Cross Keys victory, returns to the wing. It will be his first return to Pontypridd after transferring back to the Wanderers from Ponty in the summer.
In the pack Rhys Gill comes in for Nathan Trevett and Gareth Knight gets his first start of the season in the second row to partner Tom Evans.
Coach Richard Hodges also introduces Luke Fear and Andrew Cawley to the bench for the first time this season while Gareth Morris takes over the captaincy.
Glamorgan Wanderers: 15. James Loxton, 14. Steve Cullen, 13. Robin Lock, 12. Gareth Morris (capt), 11. Jason Pocock, 10. Scott Sneddon, 9. Luke Evans.
1. Rhys Gill, 2. Ryan Price, 3. Scott Andrews, 4. Gareth Knight, 5. Tom Evans, 6. Nio Aiono, 7. Lee Highgate, 8. Alistair McDonald.
Replacements: 16. Mark Sheppard, 17. Nathan Trevett, 18. Richard Thomas, 19. Mike Grimes, 20. Luke Fear, 21. Andrew Cawley, 22. Mark Roper.
As the countdown continues for RWC2015, Tournament Chief Executive Debbie Jevans visited the Millennium Stadium to discuss preparations for the eight matches and reveal the positive news that 100,000 tickets for games at the home of Welsh rugby have sold in the last seven days.
Jason Harries is targeting a first win on the World Series circuit this season with Wales. The series returns to action this weekend in Dubai where Harries is part of a team hoping to build from its efforts in round one in October.
Wales skipper Jevon Groves says his side have addressed a few points from Gold Coast and aim to 'hit the ground running' in the next two rounds of the World Series, kicking off with this weekend in Dubai before heading off to South Africa next week.
Wales Sevens manager Steff Thomas is hopeful his side can build from a quarter-final spot in the opening round of the World Series in Australia when his side take part in the forthcoming double header in Dubai and South Africa.