Glamorgan Wanderers make one change in the backs and two up front for trip to Sardis Road.
Jason Pocock, after missing the Cross Keys victory, returns to the wing. It will be his first return to Pontypridd after transferring back to the Wanderers from Ponty in the summer.
In the pack Rhys Gill comes in for Nathan Trevett and Gareth Knight gets his first start of the season in the second row to partner Tom Evans.
Coach Richard Hodges also introduces Luke Fear and Andrew Cawley to the bench for the first time this season while Gareth Morris takes over the captaincy.
Glamorgan Wanderers: 15. James Loxton, 14. Steve Cullen, 13. Robin Lock, 12. Gareth Morris (capt), 11. Jason Pocock, 10. Scott Sneddon, 9. Luke Evans.
1. Rhys Gill, 2. Ryan Price, 3. Scott Andrews, 4. Gareth Knight, 5. Tom Evans, 6. Nio Aiono, 7. Lee Highgate, 8. Alistair McDonald.
Replacements: 16. Mark Sheppard, 17. Nathan Trevett, 18. Richard Thomas, 19. Mike Grimes, 20. Luke Fear, 21. Andrew Cawley, 22. Mark Roper.
Meet the members of the WRU's inaugural Youth Board - after an online selection process which saw a host of high calibre candidates submit video applications the WRU has made its first 15 appointments.The board is made up of individuals aged between 16 and 21, and will meet for the first time at Principality Stadium on Monday 15th February.
The Wales Women's team headed to Dare Valley Country Park on a team bonding exercise as the entire squad got together for the very first time in preparation for this season's Six Nations championship which kicks off on Saturday with a clash against defending champions Ireland, in Donnybrook.
Wales Head Coach Warren Gatland discusses his team selection for the opening round of the RBS 6 Nations where he leads his side against Ireland, on Sunday. As WRU TV's Luke Brodley discovers, Gatland is fully aware of the challenges the defending champions pose
WRUTV caught up with Wales Women captain Rachel Taylor at the RBS 6 Nations launch and how a good crowd really helps boost the girls performance. Tickets for all three Women's home games at The Gnoll, Neath are available from www.wru.wales/tickets