Blues North travel to the Dragons' lair tonight hoping to extend their unbeaten run in the WRU Age Grade Championship to five matches.
Four successive wins against the Scarlets, Ospreys, Blues South and North Wales has left coach Dale McIntosh's side on top of the pile as the competition approaches its half way stage.
However, with the Dragons having registered their first win of the season - 18-12 against North Wales 10 days ago - the Blues are likely to have their work cut out.
In the other game, the Scarlets will also find it difficult on their travels - they face high-flying Blues South at Taffs Well.
Having lost their first game of the season at Blues North, the Scarlets have bagged impressive wins over the Ospreys, Dragons and North Wales to remain hot on the heels of the leaders.
Blues South too have been in decent form with two wins in four games. They lost 14-8 to the Ospreys last time out and will be keen to put their season back at track on home soil.
Blues North: C Edwards; S Webber, R Evans, T Pascoe, O Rees; L Williams, L Jones; D Harris, J Dando, T Jones, L Young, A Lee, T Davies, C Thomas, W Griff John. Replacements: B Thyre, J Elley, M Screech, J Perkins, D Jones, G Thomas, T Priest
Blues South: R Patchell; H Robinson, M Roberts, JB Bruziller (capt), C Driscoll; J Morris, T O'Brien; C Hole, J Hopkins, M Taylor, E Chilcott, B Smith, L Jones, L O'Brien, R Tucker. Replacements: R Rowley, A Rees, P Lloyd, S Bennett, R Phillips, I Matthews, J Hurley, D Young, P King
Scarlets: L Treharne; G Hunter, L Harvatt, R James, P Rushesha; J Williams, R Williams; N Bowen, S O'Leary, S Lee, D Evans, J Gardiner, R Bloomfield (capt), O Powell, C Morris. Replacements: G Thomas, A Williams, L Evans, J Iles, S Maynard, R Evans, M Jenkins
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All four regions attended a successful training camp staged last weekend at the WRU National Centre of Excellence. It was a chance for new Wales Women's head coach Rowland Phillips to deliver his key messages to players and coaches as he prepares for the new season.
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Llandovery are aiming to make it three titles in a row in this year's Foster's National 7s being held at BT Sport Cardiff Arms Park on Sunday 28 August. Drovers assistant coach Simon Davies and Lee Rees assess their sides chances
A pioneering strength and conditioning programme has been delivered to more than 8000 boys and girls at hub schools throughout Wales this season, helping to develop stronger, more flexible athletes for rugby and other sports.
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