Llanelli take their unbeaten record in the Principality Premier Division to Pandy Park where Cross Keys will be hoping to improve on their home record.
After defeating Swansea by a point, they were beaten by visitors Ebbw Vale by just two points but, with only five tries in the bag to date, they may find the Llanelli outfit too strong.
Leading try scorers Neath host Newport at the Gnoll having won their previous three home matches. The Black and Ambers have won all four matches to date and will be full of confidence against the Welsh All Blacks.
If the Scarlets slip, Aberavon are well-placed to take over at the top. They travel to a Bedwas side without a victory after drawing their first match of the season. The Wizards whitewashed Pooler last week and will be looking to hand out more misery at the Bridge Field.
Bridgend are three points ahead of visitors Swansea and a victory for the Ravens should keep them up amongst the leaders.
Both Cardiff and Ebbw Vale have had poor starts to the season but home advantage should see the Arms Park outfit home against the Steelmen. Both sides have only crossed for seven tries so it could all come down to the boot.
Bottom club Llandovery only have one bonus point to show for their efforts this season. They travel to Pontypool Park looking to improve that poor record. The Drovers only have four tries from their five outings and may be another side relying on kicks to keep them in the game.
The final match is at Sardis Road where Pontypridd entertain Glamorgan Wanderers. The Cardiff-based side can usually be relied upon to score points, but Ponty did the double over Wanderers last term.
Welsh players and management joined Deputy Minister for Sport Ken Skates at the Pierhead Building, Cardiff Bay earlier this week to reveal the Union's pioneering school-club hub initiative has been so successful the project will now almost double the scale of the original project.
The Scarlets, Newport Gwent Dragons, Cardiff Blues and the Ospreys look ahead to Judgement Day III which sees the Blues take on the Ospreys (2.30) and the Dragons tackle the Scarlets (4.45pm) at the Millennium Stadium tomorrow afternoon.
Ystradgynlais and Ynysddu played out a titanic struggle at Taffs Well in the SSE SWALEC Bowl semi-final. At the end of the game neither team could be separated after a 15-15 stalemate but Ystradgynlais go through on try count.
Blues strike first in JD III battle - Newport Gwent Dragons lock Andrew Coombs, WRU referee Dylan Llyr Jones and Cardiff Blues hooker Matthew Rees decide dressing room allocations for Judgement Day III
Wales Under 18 captain Calum Haggett has received a conditional offer to read Biomedical Science at St Anne's College, Oxford. WRU chairman Gareth Davies went to meet Calum and Coleg y Cymoedd Principal Judith Evans to wish him luck in his exams and pass on some of his personal experience.
Dodgy tattoos, carthorses, Avatar and soft chins are revealed by Wales Sevens players Tom Williams and Sam Cross as they profile the Wales Sevens squad taking part in Hong Kong this weekend in the latest round of the HSBC Sevens World Series.