Glamorgan Wanderers have suffered a blow before the derby clash against Cardiff at the Arms Park in the Principality Premiership on Saturday.
Top points scorer Scott Sneddon pulled up in training on Tuesday and Mark Roper has stepped in to the outside half berth.
However, Blues centre Dafydd Hewitt is available as is Jason Pocock who came off early last week with an eye injury.
Captain Nick Kelly returns to the second row after appearing in the back row last week but prop Scott Andrews drops down to the bench due to his commitment with the Blues U-20's. Ben Warbuton, brother of Wales U-20's captain, Sam. joins the squad for the first time this season after putting some excellent performances for Merthyr on dual registration.
The Wales Women's team headed to Dare Valley Country Park on a team bonding exercise as the entire squad got together for the very first time in preparation for this season's Six Nations championship which kicks off on Saturday with a clash against defending champions Ireland, in Donnybrook.
Wales Head Coach Warren Gatland discusses his team selection for the opening round of the RBS 6 Nations where he leads his side against Ireland, on Sunday. As WRU TV's Luke Brodley discovers, Gatland is fully aware of the challenges the defending champions pose
WRUTV caught up with Wales Women captain Rachel Taylor at the RBS 6 Nations launch and how a good crowd really helps boost the girls performance. Tickets for all three Women's home games at The Gnoll, Neath are available from www.wru.wales/tickets