David Young has made six changes for this weekend's crunch EDF Energy Cup match against the Leicester Tigers at the Arms Park.
In the backs, Jamie Roberts and Richard Mustoe, return to the starting line up. While in the back row, Robin Sowden Taylor comes in at Openside, with Martyn Williams moving down to the bench.
There is also a new front row with Taufa'ao Filise, Gareth Williams and John Yapp all starting.
Meanwhile, Seru Rabeni will make his first start of the season for Leicester Tigers
The Fijian, who returned from suspension to appear as a second-half replacement in last weekend's nine-try win over Benetton Treviso in the Heineken Cup, is named on the wing by head coach Heyneke Meyer.
Johne Murphy, who scored a hat-trick of tries in Italy last Saturday, moves to full-back, while Derick Hougaard returns at fly-half and Toby Flood moves to inside centre.
George Chuter and Boris Stankovich return to the front row and Richard Blaze is named in the second row as Ben Kay moves to the replacements' bench.
"We made a good start to the competition with the away win against Bath," said Meyer. "Now we have another tough game."
The Cardiff Blues will be aiming to send away the Leicester Tigers in this crucial EDF Energy Cup game and tickets for the match are still available.
Junor tickets priced at just £5. Tickets for adults are priced at £16 for terrace or family stand and £20 for grandstand. Tickets can be purchased by calling 029 2030 2030 or online at www.cardiffblues.com/tickets
Cardiff Blues: Ben Blair; Leigh Halfpenny, Jamie Robinson, Jamie Roberts, Richard Mustoe; Nick Robinson, Jason Spice; John Yapp, Gareth Williams, Taufa'ao Filise, Deiniol Jones, Paul Tito (capt), Maama Molitika, Robin Sowden Taylor, Andy Powell.
Replacements: Gary Powell, T Rhys Thomas, Scott Morgan, Martyn Williams, Richie Rees, Ceri Sweeney, Tom Shanklin.
Leicester 15 Johne Murphy 14 Seru Rabeni 13 Danny Hipkiss 12 Toby Flood 11 Matt Smith 10 Derick Hougaard 9 Harry Ellis 1 Boris Stankovich2 George Chuter 3 Julian White 4 Richard Blaze 5 Marco Wentzel 6 Martin Corry (captain) 7 Tom Croft 8 Jordan Crane
Replacements 16 Benjamin Kayser 17 Dan Cole 18 Ben Kay 19 Brett Deacon 20 Julien Dupuy 21 Ayoola Erinle 22 Tom Varndell
Principality Stadium will host the UEFA Champions League Final in six weeks' time. WRU chairman Gareth Davies, Football Association of Wales chief executive Jonathan Ford and Ambassador Ian Rush joined young sports fans at the trophy arrival at the venue to celebrate the magnitude of the event on Saturday 3rd June (kick-off 19.45).
British and Irish Lions captain Sam Warburton is looking forward to bringing together players from Ireland, Scotland, England and Wales for the biggest challenge of their careers - a series against world champions, New Zealand.
For the fifth year running, Wales referee Nigel Owens will be in charge of proceedings at Judgement Day V at Principality Stadium. It promises to be 'extra special' for the Wales' favourite ref, as he will be making his 150th appearance in the league.
There will be no shortage of inside knowledge from Bowl Finalists Caerphilly and Amman United when they face each other on Sunday at National Finals Day. Caerphilly hooker Rhys Cleverly knows the Principality Stadium pitch better than most as a matchday groundsman, while Amman United can look to Wales' record try scorer Shane Williams for some helpful advice.
Two hundred and 40 teams competed in the inaugural Urdd WRU 7s held at Pencoed last week with Welsh internationals Steff Andrews and Jasmine Joyce impressed with the talent on display, as was Urdd chief executive, Sioned Hughes.
The countdown is on for Judgement Day V as tickets for the big day at Principality Stadium soar through the 50,000 mark. Players and coaches alike are bursting at the seams to play in the double header with Dragons coach Kingsley Jones claiming there is a 'real buzz' about the event.
WRU TV went behind the scenes when the four regions got together to test their skill set for the BBC's Scrum V Live rugby show, at the WRU National Centre of Excellene in the build up to Judgement Day V. Blues' Matthew Morgan was one of the stars of the show while the Dragons' Cory Hill proved a surprise package...the full set of results will be revealed on tv screens on matchday
Wales assistant coach Richie Pugh is confident his side can cause a few headaches in the Hong Kong Sevens this weekend. In a tough group, Wales kick off their campaign against New Zealand on Friday before playing Japan and Fiji, who are chasing their third consecutive Hong Kong title, on Saturday.
Bedwas had to overcome a stubborn Carmarthen Quins side before winning the Foster's Challenge Cup final in Bridgend with a 23-18 victory. Bedwas captain Nicky Griffiths pays tribute to his side who have claimed the club's first piece of silverware in the modern era.
Team coach Brett Davey is aiming to keep his unbeaten run in cup finals at Principality Stadium intact when his side take on Amman United in the WRU Bowl final, after he guided Caerphilly to a 20-14 win against Cilfynydd in the semi-finals.
Penallta are hoping to go one step further than last season when falling to Bedlinog in the WRU Plate Final. After a titanic struggle against Nant Conwy, they have given themselves a great chance, after a hard fought 18-13 semi-final victory.