The top two teams in the Principality Premiership meet at Rodney Parade where Newport entertain Llanelli. The Black and Ambers are just three points adrift behind the Scarlets and victory would see them top of the table.
Llandovery have a tough task trying to follow last week's first win of the season with another four pointer. They meet fifth-placed Neath at their Church Bank ground but will be confident of causing an upset because the Welsh All Blacks have been beaten on their last two league outings.
There is a relegation battle at Bedwas where Cross Keys are the visitors. Both clubs need points to steer themselves away from the foot of the table and Bridge Field may not be for the faint-hearted but Keys are in form and may just do enough for victory.
Despite having lost three times already this season Aberavon are in third spot. With four home victories to date they will be ready for the challenge from Bridgend and should be strong enough to cement their position.
Cardiff and Glamorgan Wanderers are bracketed together in mid-table on 19 points. Wanderers have managed just the one away victory this term but they beat Cardiff at the Arms Park last season and will be all out to repeat that result so it could be a close call.
Pontypool have had a difficult start to life back in the top flight and they host Pontypridd looking for the victory that will move them away from the drop zone.
In the final match Ebbw Vale travel to Swansea with the Steelmen fully eight points better off than the All Whites. Vale have won three out four away games this season and could well come up with another victory.
Wales U20 captain Tom Phillips and performance psychologist Dr Rich Neil explain why spending three days at Monmouth RFC has further strengthened the togetherness of the squad ahead of the #WorldRugbyU20s
Alongside Scarlets flanker James Davies and Cardiff Blues centre Cory Allen, three Wales Sevens core players have made the extended training squad for GB Sevens. Wales Head coach Gareth Williams tells WRU TV's Graeme Gillespie why Luke Treharne, Sam Cross and Luke Morgan earned selection in the initial training squad for Rio.
Wales Sevens head coach Gareth Williams tells WRU TV's Graeme Gillespie he has had to overcome a number of injuries before naming a competitive squad for this weekend's penultimate round of the World Series in Paris.
Merthyr were officially crowned champions of the SSE SWALEC Championship at Dowlais on Saturday where captain Andy Powell paid tribute to his side who have earned promotion to the Principality Premiership
Coleg y Cymoedd's season has had a spectacular ending with victory in two cup finals and a massive victory over one of the best rugby playing schools in the world - Welsh coach Warren Gatland's old alma mater, Hamilton Boys' High School.
WRU chief executive Martyn Phillips hosted the second meeting of the WRU Youth Board last weekend ahead of the Judgement Day IV regional double-header. Tthe board, made up of 15 under-21-year-olds from around Wales, heard presentations from head of participation Ryan Jones, policy and integrity manager Jeremy Rogers and national women's rugby manager Caroline Spanton, with Pro Rugby Wales CEO Mark Davies also on hand to hear the range of views aired.
Wales duo Rhun Williams and Liam Belcher, who makes a welcome return after five months of injury woe, look ahead to next month's World Rugby U20 Championship in Manchester where they will face Ireland, Georgia and New Zealand.