Tom Willis returns for his first taste of Heineken Cup rugby for the Dragons against Glasgow Warriors on Saturday.
Dragons skipper Willis was rested for their EDF Energy Cup win over Newcastle Falcons last weekend.
But the New Zealand hooker is back to lead the Gwent region for their European opener in Pool 5.
Willis said: "It's great to be back for arguably the finest rugby tournament around and one in which we truly will be tested by some of the finest teams in Europe.
"We've got a very challenging pool but our preparation has been good and has put an extra spring in the lads step and brought an extra edge to training.
"It was great last week for the team to grind out another win and continue to build the momentum we've gained so far."
Wales prop Rhys Thomas, lock Luke Charteris and fly-half James Arlidge also return for the clash at Rodney Parade.
Newport Gwent Dragons: Forwards: Steve Jones, Aaron Coundley, Andrew Hall, Adam Jones, Joe Bearman, Rhys Thomas, Lewis Evans, Luke Charteris, Colin Charvis, Adam Black, Tom Willis (captain), Grant Webb, Dan Lydiate, Ricahrd Parks, Jamie Ringer. Backs: Gareth Wyatt, Phillip Dollman, Wayne Evans, Marc Stcherbina, Robert Lewis, Rory Sidey, Richard Fussell, Jason Tovey, Shaun Connor, James Arlidge, Ashley Smith, Rhodri Gomer Davies, Tal Selley.
When the Wales squad were asked to nominate individuals who played a big part in their early playing days, Wales and Dragons full back and wing Hallam Amos thought of his former Monmouth School rugby coach John Bevan.
Sam Cross and Luke Treharne have been named as co-captains of the Wales Sevens side as head coach Gareth Williams names his 12-man squad to play in the first leg of the HSBC World Series in Dubai next weekend.
Bedwas head coach Steve Law and players Nicky Griffiths and Alun Rees extol the virtues of the close knit club as they prepare to host third place RGC 1404 - who are one place head of them on the Principality Premiership points table - on Saturday.
Many of the Wales squad have said Diolch (thank you) to someone who played an important part in their early playing days by nominating them to be invited to the Wales v South Africa match. One person, Gowerton Comprehensive geography teacher Mr Dean Mason was nominated by two of his former pupils, Dan Biggar and Sam Davies.
The second WRU disability rugby pilot has been delivered, this time in Caerphilly schools, culminating in a festival at the Caerphilly Centre of Sporting Excellence, Ystrad Mynach tomorrow. Plans are in place to set up a Disability Rugby Club in Newbridge to provide long-term playing opportunities.
WRU TV: Hear from inside the Wales camp as Neil Jenkins discusses this weekend's clash with South Africa and how the squad are looking to put in a strong performance to round of the 2016 Under Armour Series