Ospreys Coach Sean Holley knows his side must rise to the challenge of facing English opposition they Worcester Warriors in the EDF Energy Cup this weekend
He said: "After a demanding fortnight in the Heineken Cup, we have to switch our focus to the EDF Energy Cup this weekend, and the unique and very different challenges which this competition presents. Worcester are a top side with some big names in the likes of Chris Latham, Pat Sanderson and Sam Tuitupou. They go into Sunday's game in a rich vein of form having scored over 100 points in their last two games, and they also achieved an excellent bonus point win in their first pool match in this competition, against London Irish, so we are under no illusions as to how Mike Ruddock and his team will be preparing for this game.
"We are delighted to welcome back Nikki Walker, James Hook, Lyndon Bateman and Jamie Nutbrown after injury, it's always good to see players returning to action and increasing the options available in the squad for a match-day. Jamie in particular is desperate to pull the shirt on again having only figured in two games for us to date, and we are excited by that prospect.
"We've selected a very experienced side, with 16 of the 22 having more than 50 Ospreys appearances to their name. We will need all of that experience for this challenge, but we are all looking forward to it immensely and hope that we'll have a big crowd behind as we look to build on last week.
"Our results have been good of late, but we feel that we can still improve in lots of aspects of our game. The players have been extremely diligent and focused this week and want to take a step closer to retaining this trophy.
"As we prepare for this game, we must congratulate our players selected for the Autumn International series this week. It is a credit to our organisation, and in particular to our players, that we can celebrate 50 per cent of the extended Wales squad coming from our regional family."
The Ospreys welcome Jamie Nutbrown, James Hook, Lyndon Bateman and Nikki Walker back from injury for the EDF Cup game, Walker back far earlier than expected.
Gavin Henson also returns from his two-match Ospreys ban, the centre eager to get game time having been named in Wales' squad for the autumn Tests.
Warriors have Matthew Jones at fly-half for a return to his old club.
The former Welsh international fly-half has recovered from an ankle injury picked up in Bucharest.
Chris Latham returns to the Worcester Warriors starting 15, replacing Loki Crighton, and is one of three changes from the team that won in Bucharest in the European Challenge Cup.
Chris Pennell comes in on the wing and Jake Abbott is in the back row replacing Miles Benjamin and Tom Wood who both have shoulder injuries.
Ospreys: Lee Byrne; Nikki Walker, Tommy Bowe, Gavin Henson, Shane Williams; James Hook, Rhys Webb; Duncan Jones (capt), Huw Bennett, Andrew Millward, Ian Gough, Lyndon Bateman, Tom Smith, Steve Tandy, Filo Tiatia.
Replacements: Richard Hibbard, Adam Jones, Alun Wyn Jones, Ryan Jones, Jamie Nutbrown, Dan Biggar, Andrew Bishop.
Warriors: Chris Latham; Rico Gear, Alex Grove, Sam Tuitupou, Chris Pennell; Matthew Jones, Ryan Powell; Matt Mullan, Aleki Lutui, Tevita Taumoepeau, Greg Rawlinson (capt), Craig Gillies, Matt Cox, Jake Abbott, Netani Talei.
Replacements: Darren Morris, Shaun Ruwers, Graham Kitchener, Rob Wood, Matt Powell, Loki Crichton, Charlie Fellows.
Referee: David Rose
Ospreys full-back Lee Byrne says they are determined to beat Group C leaders Worcester as they seek to retain their EDF Energy Cup crown.
Wales and Ospreys back row James King, who came through the North Wales age grade system, nominated North Wales Regional Community Rugby Manager Marc Roberts, in the WRU's 'Diolch' initiative where squad players thanked those who played a part in their rise to the top.
Beating Merthyr has boosted Carmarthen Quins hopes of reaching a top eight spot in the Principality Premiership. Quins captain Haydn Pugh is delighted with his team's progress and is determined that everyone from the Under 6s through to the senior team, enjoys the ride.
When the Wales squad were asked to nominate individuals who played a big part in their early playing days, Wales and Dragons full back and wing Hallam Amos thought of his former Monmouth School rugby coach John Bevan.
Sam Cross and Luke Treharne have been named as co-captains of the Wales Sevens side as head coach Gareth Williams names his 12-man squad to play in the first leg of the HSBC World Series in Dubai next weekend.
Bedwas head coach Steve Law and players Nicky Griffiths and Alun Rees extol the virtues of the close knit club as they prepare to host third place RGC 1404 - who are one place head of them on the Principality Premiership points table - on Saturday.
Many of the Wales squad have said Diolch (thank you) to someone who played an important part in their early playing days by nominating them to be invited to the Wales v South Africa match. One person, Gowerton Comprehensive geography teacher Mr Dean Mason was nominated by two of his former pupils, Dan Biggar and Sam Davies.
The second WRU disability rugby pilot has been delivered, this time in Caerphilly schools, culminating in a festival at the Caerphilly Centre of Sporting Excellence, Ystrad Mynach tomorrow. Plans are in place to set up a Disability Rugby Club in Newbridge to provide long-term playing opportunities.
WRU TV: Hear from inside the Wales camp as Neil Jenkins discusses this weekend's clash with South Africa and how the squad are looking to put in a strong performance to round of the 2016 Under Armour Series