Scotland squad lock Scott McLeod is in the Scarlets starting line-up whilst fullback Barry Davies makes his first start since the new year after injury. Young scrum half Liam Davies makes his first start of the season.
Changes up front from the game against Leinster bring in Aled Gravelle, Adam Jones and Inoke Afeaki.
The Scarlets won the reverse fixture at Stradey Park in September 31-17 as young wing Darren Daniel ran in a hat-trick of tries.
Glasgow: Lamont, O'Hare, Morrison, Henderson, Evans, Parks, Beveridge, Va'a, Thomson, Low, Newman, Kellock (capt), Petrie, Barclay, Beattie
Replacements: Milligan, Tkachuk, Turner, Swindall, Pinder, Gregor, Barrow
Scarlets: B Davies; D James, R King, M Watkins, D Daniel; C Thomas, L Davies; I Thomas, A Gravelle, C Dunlea, A Jones, S McLeod, I Afeaki, D Jones, J Bater (capt)
Replacements: M Rees, D Manu, N Thomas, G Thomas, C Stuart-Smith, G Evans, M Stoddard