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The Irish province travel to the home of the 2001 and 2002 champions for their first tournament match as holders of European club rugby's most coveted trophy, with Leicester Tigers making the return trip to the Thomond Park fortress in Round 6.
The fixtures, dates, kick-off times and host TV broadcasters for the first four Rounds of the 12th Heineken Cup tournament, released by ERC today (Thursday, 20 July), see English champions Sale Sharks also on the road in Round 1 taking on the Ospreys at the Liberty Stadium in Pool 3 on the opening night.
French champions Biarritz Olympique will have home advantage against 2000 Heineken Cup winners Northampton Saints when the opening shots are fired in Pool 6 with top Scottish team Edinburgh Gunners travelling to the South of France to meet Agen, who return to the tournament after a two year absence, in Pool 2.
Welsh No 1 seeds Cardiff Blues will also travel to France to tackle Bourgoin in Pool 4 with Italian standard bearers Benetton Treviso and Irish top seeds Ulster both at home to French opposition, Perpignan going to Treviso and treble champions Toulouse to Belfast.
Tournament newcomers Overmach Rugby Parma will get their first taste of Heineken Cup action away to Border Reivers in Pool 6.
Details of the additional TV coverage of Rounds 1 to 4 by ERC's broadcast partners, France Televisions, Groupe Canal +, Sky Sports, RTE TV and S4C, including all live, delayed and highlights broadcasts, will be announced shortly.