The Ravens notched a narrow 17-18 victory over Pontypridd in a rearranged fixture on Wednesday to go level on points with run-away leaders Neath who hold four games in hand.
Llandovery meanwhile are without a win in over a month and find themselves third from bottom and very much fighting for their survival.
Cardiff, who beat Maesteg 17-36 in mid-week, play host to Pontypool in the Capital in a crunch game for two clubs desperate to avoid the drop.
That Maesteg win may have lifted Cardiff off the foot of the table but the Arms Park side need more points if they are to defy the critics and avoid an embarrassing relegation.
Third-placed Aberavon take on Welsh Cup holders Llanelli at the Talbot Athletic Ground as they chase Bridgend.
The Wizards hold a game in hand over the Ravens but will need the Brewery Field outfit to slip up if they are to steal in on second place.
Carmarthen entertain reigning champions and runaway leaders Neath who have lost only once this season.
The Quins are currently in eleventh spot and three more points should be enough to secure their top-flight future beyond doubt.
But as the Welsh All Blacks race to a second title in as many years they don't look like dropping points.
At Pandy Park Cross Keys clash with visiting Glamorgan Wanderers with both sides comfortable in mid-table.
The Keys have had a fine season and are still on course to equal or better last season's sixth-place finish.
The Wanderers have performed well in their return season to Premiership rugby and now have a platform on which to build for a top-flight future.
Bottom-placed Ebbw Vale travel to Sardis Road to front up to Pontypridd in a must win game for both sides.
The Steelmen desperately need points as they fight to avoid division one rugby next term while Ponty have games in hand over their rivals and are still chasing second spot.
Elsewhere Newport travel to Bedwas and on the coast Swansea welcome Maesteg to St Helen's.